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Query: ITPA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ITPA 0 0.554 0.970 -0.680 -0.090

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ITPA Ubiquitylation K18 0.644 _IVFVTGNAK(gl)K_
ITPA Ubiquitylation K19 0.644 _IVFVTGNAK(gl)K_

Background Information for ITPA:





Protein-protein Interactions for ITPA

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAMTS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCL22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FERMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOR1AIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSHR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ITPA

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ITPase-like_fam IPR029001 0.17


Protein complexes (CORUM database) featuring ITPA

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ITPA

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0051276 chromosome organization Database 0.1
Category members Pathway Pathway_77 KEGG_DRUG_METABOLISM_OTHER_ENZYMES 0 0
Category members GO Category GO:0035870 dITP diphosphatase activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0047429 nucleoside-triphosphate diphosphatase activity Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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