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Query: DHODH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHODH 0 -1.561 -0.520 0.170 -1.249 -0.292

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHODH Ubiquitylation K235 -0.190 _LLTK(gl)VLQER_

Background Information for DHODH:


Pubmed-DHODH »
Uniprot-DHODH »
Biogrid-DHODH »
ProteomicsDB-DHODH »

Tumorportal-DHODH »
COSMIC-DHODH »
GenomeRNAi-DHODH »
Genecards-DHODH


Protein-protein Interactions for DHODH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait VAC14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHODH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Dihydroorotate_DH_1_2 IPR012135 0


Protein complexes (CORUM database) featuring DHODH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DHODH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0007565 female pregnancy Database 0.19
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0046134 pyrimidine nucleoside biosynthetic process Database 0.05
Category members GO Category GO:0010181 FMN binding Database 0.04
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_278 REACTOME_PYRIMIDINE_METABOLISM 0 0
Category members GO Category GO:0004152 dihydroorotate dehydrogenase activity Database 0
Category members GO Category GO:0004158 dihydroorotate oxidase activity Database 0
Category members GO Category GO:0006206 pyrimidine nucleobase metabolic process Database 0
Category members GO Category GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process Database 0
Category members GO Category GO:0006222 UMP biosynthetic process Database 0
Category members GO Category GO:0007595 lactation Database 0
Category members GO Category GO:0008144 drug binding Database 0
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0031000 response to caffeine Database 0
Category members GO Category GO:0042594 response to starvation Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0044205 'de novo' UMP biosynthetic process Database 0
Category members GO Category GO:0048039 ubiquinone binding Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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