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Query: NT5C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NT5C 0 0.113 -0.270 0.710

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NT5C Phosphorylation S182 0.253 _LLS(ph)WSDNWR_
NT5C Ubiquitylation K194 -0.850 _EILDSK(gl)R_

Background Information for NT5C:


Pubmed-NT5C »
Uniprot-NT5C »
Biogrid-NT5C »
ProteomicsDB-NT5C »

Tumorportal-NT5C »
COSMIC-NT5C »
GenomeRNAi-NT5C »
Genecards-NT5C


Protein-protein Interactions for NT5C
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARPC1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf86 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NT5C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRPD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF581 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NT5C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members 5'(3')-deoxyribonucleotidase IPR010708 0
Category members HAD-like_dom IPR023214 0


Protein complexes (CORUM database) featuring NT5C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NT5C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0008253 5'-nucleotidase activity Database 0.17
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_278 REACTOME_PYRIMIDINE_METABOLISM 0 0
Category members Pathway Pathway_281 KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM 0 0
Category members Pathway Pathway_284 REACTOME_PURINE_CATABOLISM 0 0
Category members Pathway Pathway_298 REACTOME_PYRIMIDINE_CATABOLISM 0 0
Category members GO Category GO:0006195 purine nucleotide catabolic process Database 0
Category members GO Category GO:0006206 pyrimidine nucleobase metabolic process Database 0
Category members GO Category GO:0008252 nucleotidase activity Database 0
Category members GO Category GO:0009223 pyrimidine deoxyribonucleotide catabolic process Database 0
Category members GO Category GO:0009264 deoxyribonucleotide catabolic process Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0046135 pyrimidine nucleoside catabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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