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Query: ADSS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADSS 0 0.436 -0.040 -0.580 -0.323

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADSS Ubiquitylation K447 0.344 0.415 _WIGVGK(gl)SR_
ADSS Ubiquitylation K125 0.267 _GLEGWEK(gl)R_
ADSS Ubiquitylation K173 -0.819 -0.534 _GIGPVYSSK(gl)AAR_
ADSS Ubiquitylation K118 -0.813 _GK(gl)GLEGWEK_
ADSS Ubiquitylation K157 -0.039 _QEQAGK(gl)NLGTTK_
ADSS Ubiquitylation K419 -0.511 _AFK(gl)ELPVNAQNYVR_

Background Information for ADSS:


Pubmed-ADSS »
Uniprot-ADSS »
Biogrid-ADSS »
ProteomicsDB-ADSS »

Tumorportal-ADSS »
COSMIC-ADSS »
GenomeRNAi-ADSS »
Genecards-ADSS


Protein-protein Interactions for ADSS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LGALS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMYD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ADSS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Adenylosuccinate_synthetase IPR001114 0


Protein complexes (CORUM database) featuring ADSS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ADSS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members Pathway Pathway_273 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS 0 0.23
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members GO Category GO:0006531 aspartate metabolic process Database 0.2
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0009168 purine ribonucleoside monophosphate biosynthetic process Database 0.12
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members GO Category GO:0071257 cellular response to electrical stimulus Database 0.08
Category members GO Category GO:0042301 phosphate ion binding Database 0.07
Category members Pathway Pathway_272 KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 0 0.04
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0002376 immune system process Database 0
Category members GO Category GO:0004019 adenylosuccinate synthase activity Database 0
Category members GO Category GO:0006164 purine nucleotide biosynthetic process Database 0
Category members GO Category GO:0006167 AMP biosynthetic process Database 0
Category members GO Category GO:0014074 response to purine-containing compound Database 0
Category members GO Category GO:0044208 'de novo' AMP biosynthetic process Database 0
Category members GO Category GO:0046040 IMP metabolic process Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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