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Query: ADK

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADK 0 1.113 0.210 0.300

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADK Ubiquitylation K256 0.320 0.493 _EQGFETK(gl)DIKEIAK_
ADK Ubiquitylation K117 -0.137 _FGEILK(gl)R_

Background Information for ADK:


Pubmed-ADK »
Uniprot-ADK »
Biogrid-ADK »
ProteomicsDB-ADK »

Tumorportal-ADK »
COSMIC-ADK »
GenomeRNAi-ADK »
Genecards-ADK


Protein-protein Interactions for ADK
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ADK
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PfkB_dom IPR011611 0
Category members Ribokinase-like IPR029056 0


Protein complexes (CORUM database) featuring ADK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ADK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members GO Category GO:0032922 circadian regulation of gene expression Database 0.21
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members GO Category GO:0044209 AMP salvage Database 0.11
Category members GO Category GO:0042102 positive regulation of T cell proliferation Database 0.04
Category members GO Category GO:0010613 positive regulation of cardiac muscle hypertrophy Database 0.04
Category members Pathway Pathway_205 REACTOME_PURINE_SALVAGE 0 0
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Disease phenotype Autosomal_Recessive_Mental_Retardation Autosomal Recessive Mental Retardation Database 0
Category members GO Category GO:0006166 purine ribonucleoside salvage Database 0
Category members GO Category GO:0009156 ribonucleoside monophosphate biosynthetic process Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0043101 purine-containing compound salvage Database 0
Category members GO Category GO:0044342 type B pancreatic cell proliferation Database 0
Category members GO Category GO:0046085 adenosine metabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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