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Autosomal Recessive Mental Retardation
(Autosomal_Recessive_Mental_Retardation)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ASCC3 6 -2.500 4.400 1.365 -0.715 -0.792 0.712 0.535
ASCC3 6 2.300 -1.140 1.365 -0.715 -0.792 0.712 0.535
LARP7 3 -0.820 2.570 0.263 -0.150 0.109
EEF1B2 2 1.060 -0.810 -0.092 0.144 -0.187 -0.001 0.028
EEF1B2 2 1.400 -0.530 -0.092 0.144 -0.187 -0.001 0.028
PARP1 2
PARP1 2 -0.200 0.357 0.412 0.442 0.293
WDR45B 1 2.620 -1.430
UBR7 0 -0.600 1.020
POLR3B 0 0.540 -0.900 1.056 0.594
ZCCHC8 0 0.230 -0.260 -1.876 -3.179 -1.337 -1.994 -1.038
INPP4A 0
TAF2 0 -0.530 1.000 0.642 0.344
KDM5A 0 0.183 -0.131
TRMT1 0 -0.640 0.800 -1.192
TRMT1 0 -0.640 0.800 -0.296
CASP2 0 0.980 -1.120
GON4L 0 0.300 -0.370
GON4L 0 0.300 -0.370 1.095 -0.247
ELP2 0 0.130 -0.470 0.142
SLC31A1 0
SCAPER 0 -0.980 0.880
CCNA2 0 -0.530 0.260
ERLIN2 0 0.000 -0.170 0.649 0.355
ARL14EP 0 1.570 -0.450
ADK 0 0.210 0.300
KIF7 0 -0.700 0.600 0.688
KIF7 0 0.280 -0.500 0.688
FASN 0 -0.350 -0.530 -0.550 -0.478 -0.892 -0.134 0.004
MAN1B1 0 -1.220 1.640
RGS7 0 0.820 -0.610
ZBTB40 0 -0.680 0.720 -0.044
RABL6 0 -0.510 0.120

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADK Ubiquitylation K117 -0.137 _FGEILK(gl)R_
ADK Ubiquitylation K256 0.320 0.493 _EQGFETK(gl)DIKEIAK_
ARL14EP Ubiquitylation K83 -0.011 _SCCDPFNIHK(gl)K_
ARL14EP Ubiquitylation K84 -0.011 _SCCDPFNIHK(gl)K_
ARL14EP Ubiquitylation K169 -1.065 _QTEFAPETGK(gl)R_
ARL14EP Ubiquitylation K193 -2.875 _QVIPAKSK(gl)_
ASCC3 Ubiquitylation K197 4.182 1.860 _TISLDYK(gl)K_
ASCC3 Ubiquitylation K198 4.471 1.560 _TISLDYKK(gl)_
ASCC3 Ubiquitylation K311 2.994 0.702 _FQALQDNCK(gl)K_
ASCC3 Ubiquitylation K312 2.919 0.713 _FQALQDNCKK(gl)_
ASCC3 Ubiquitylation K572 0.464 _ELTGDMQLSK(gl)SEILR_
ASCC3 Ubiquitylation K1369 -0.219 _VFNK(gl)YPTSK_
ASCC3 Ubiquitylation K1382 -1.028 _AVYIAPLK(gl)ALVR_
ASCC3 Ubiquitylation K1416 -1.216 _VIELTGDVTPDMK(gl)SIAK_
ASCC3 Ubiquitylation K1543 -0.021 _MASMNK(gl)PAFQAIR_
ASCC3 Ubiquitylation K1671 1.280 -0.224 _GTEYYDGK(gl)TR_
ASCC3 Ubiquitylation K2097 1.163 _GK(gl)PESCAVTPR_
ASCC3 Phosphorylation S2195 2.989 2.370 _VSDS(ph)LTDLALK_
CASP2 Phosphorylation S340 -0.347 -1.529 _NHAGS(ph)PGCEESDAGKEK_
CCNA2 Ubiquitylation K54 -0.746 _AALAVLK(gl)SGNPR_
CCNA2 Ubiquitylation K68 -1.274 _GLAQQQRPK(gl)TR_
EEF1B2 Phosphorylation S106 -0.152 -0.007 _YGPADVEDTTGSGATDSKDDDDIDLFGS(ph)DDEEESEEAKR_
EEF1B2 Ubiquitylation K186 2.509 4.473 _LVPVGYGIKK(gl)_
ELP2 Ubiquitylation K484 -0.739 _LFAPWK(gl)R_
ELP2 Ubiquitylation K524 0.072 -0.086 _FQFVSGADEK(gl)VLR_
ERLIN2 Ubiquitylation K190 0.454 _NYELMESEK(gl)TK_
ERLIN2 Ubiquitylation K192 -0.074 _TK(gl)LLIAAQK_
ERLIN2 Ubiquitylation K199 -0.112 _LLIAAQK(gl)QK_
ERLIN2 Ubiquitylation K201 -0.188 _LLIAAQKQK(gl)_
FASN Ubiquitylation K41 -0.859 -0.543 _WK(gl)AGLYGLPR_
FASN Phosphorylation S207 0.105 0.507 _LGMLS(ph)PEGTCK_
FASN Ubiquitylation K213 -0.346 -0.011 _LGMLSPEGTCK(gl)AFDTAGNGYCR_
FASN Ubiquitylation K235 -0.149 0.117 _SEGVVAVLLTK(gl)K_
FASN Ubiquitylation K236 -0.149 -0.024 _SEGVVAVLLTKK(gl)_
FASN Ubiquitylation K326 0.372 _QEPLLIGSTK(gl)SNM(ox)GHPEPASGLAALAK_
FASN Ubiquitylation K436 -0.250 _TPEAVQK(gl)LLEQGLR_
FASN Ubiquitylation K528 -0.086 -0.587 _SDEAVK(gl)PFGLK_
FASN Ubiquitylation K673 0.201 0.234 _K(gl)EGVFAK(gl)EVR_
FASN Ubiquitylation K776 -1.050 _GLK(gl)PSCTIIPLMK_
FASN Phosphorylation S974 -1.491 -0.989 _LFDHPES(ph)PTPNPTEPLFLAQAEVYK_
FASN Phosphorylation T976 -1.624 -1.495 _LFDHPESPT(ph)PNPTEPLFLAQAEVYK_
FASN Phosphorylation S1028 0.133 -0.404 _DNWVS(ph)FM(ox)DTMLQMSILGSAK_
FASN Ubiquitylation K1065 -1.459 _QK(gl)LYTLQDK_
FASN Ubiquitylation K1072 0.386 0.144 _LYTLQDK(gl)AQVADVVVSR_
FASN Ubiquitylation K1142 0.056 0.226 _AALQEELQLCK(gl)GLVQALQTK_
FASN Ubiquitylation K1151 0.234 -0.094 _GLVQALQTK(gl)VTQQGLK_
FASN Ubiquitylation K1158 -0.496 -0.468 _VTQQGLK(gl)MVVPGLDGAQIPRDPSQQELPR_
FASN Ubiquitylation K1239 -0.362 _ACLDTAVENMPSLK(gl)MK_
FASN Ubiquitylation K1241 -0.510 -0.579 _ACLDTAVENMPSLKMK(gl)_
FASN Phosphorylation S1411 -0.978 _RPTPQDS(ph)PIFLPVDDTSFR_
FASN Ubiquitylation K1582 -1.228 -2.032 _DIMLATGK(gl)LSPDAIPGK_
FASN Ubiquitylation K1704 -0.247 _VFTTVGSAEK(gl)R_
FASN Ubiquitylation K1847 0.204 _YMAQGK(gl)HIGK_
FASN Ubiquitylation K1866 -1.615 -1.050 _VVVQVLAEEPEAVLK(gl)GAKPK_
FASN Ubiquitylation K1869 -0.967 _VVVQVLAEEPEAVLKGAK(gl)_
FASN Ubiquitylation K1871 -0.926 _GAK(gl)PKLM(ox)SAISK_
FASN Ubiquitylation K1878 0.194 -0.638 _LM(ox)SAISK(gl)TFCPAHK_
FASN Ubiquitylation K1911 -0.329 0.084 _GVQK(gl)LVLTSR_
FASN Ubiquitylation K1927 -0.254 -0.492 _TGYQAK(gl)QVR_
FASN Ubiquitylation K1993 -1.641 _DGLLENQTPEFFQDVCK(gl)PK_
FASN Phosphorylation S2198 -1.105 -1.296 _ADEAS(ph)ELACPT(ph)PK_
FASN Phosphorylation T2204 -0.587 -0.205 _ADEASELACPT(ph)PKEDGLAQQQTQLNLR_
FASN Ubiquitylation K2391 -0.844 -0.267 _VLEALLPLK(gl)GLEER_
FASN Ubiquitylation K2426 -0.591 0.390 _SFYYK(gl)LR_
FASN Ubiquitylation K2438 -0.623 -0.362 _AK(gl)YHGNVM(ox)LLR_
FASN Ubiquitylation K2449 -0.636 0.411 _AK(gl)TGGAYGEDLGADYNLSQVCDGK_
GON4L Phosphorylation S346 -0.521 _GVVIPTWNIS(ph)PIKK_
GON4L Phosphorylation S803 -0.117 -0.339 _LEPQELS(ph)PLSATVFPK_
INPP4A Phosphorylation S487 0.497 0.637 _AS(ph)PTSTEEEQVMLR_
KDM5A Ubiquitylation K135 -0.691 _GGFEMVTK(gl)EK_
KDM5A Ubiquitylation K137 -0.691 _GGFEMVTK(gl)EK_
KDM5A Ubiquitylation K159 -0.589 _GTGSLLK(gl)SHYER_
KDM5A Ubiquitylation K805 -0.328 _EAETCASVAQLLLSKK(gl)_
KDM5A Phosphorylation S1111 -0.424 0.369 _DLDLEPLS(ph)DLEEGLEETR_
KDM5A Phosphorylation S1666 -1.341 _KQGPVS(ph)PGPAPPPSFIMSYK_
KIF7 Ubiquitylation K1208 0.476 _YMWINQELK(gl)QK_
LARP7 Phosphorylation S261 -0.075 0.035 _SRPTSEGS(ph)DIESTEPQK_
LARP7 Phosphorylation S298 1.307 0.810 _RS(ph)SSEDAESLAPR_
LARP7 Phosphorylation S299 1.228 _SS(ph)SEDAESLAPR_
LARP7 Phosphorylation S300 1.566 0.941 _KRSSS(ph)EDAESLAPR_
LARP7 Phosphorylation S337 3.160 _DIEIS(ph)TEEEKDTGDLKDSSLLK_
LARP7 Phosphorylation T338 2.759 3.424 _DIEIST(ph)EEEKDTGDLKDSSLLK_
LARP7 Phosphorylation S350 2.345 _DIEISTEEEKDTGDLKDS(ph)SLLK_
LARP7 Phosphorylation S351 0.886 _DIEISTEEEKDTGDLKDSS(ph)LLK_
MAN1B1 Ubiquitylation K562 -1.233 _DVEVK(gl)PADR_
PARP1 Phosphorylation S41 -0.803 _MAIMVQS(ph)PMFDGK_
PARP1 Ubiquitylation K84 1.223 _WDDQQK(gl)VK_
PARP1 Ubiquitylation K86 1.058 _VK(gl)KTAEAGGVTGK_
PARP1 Ubiquitylation K87 1.058 _VK(gl)KTAEAGGVTGK_
PARP1 Ubiquitylation K97 1.386 0.406 _TAEAGGVTGK(gl)GQDGIGSK_
PARP1 Ubiquitylation K105 0.828 _GQDGIGSK(gl)AEK_
PARP1 Ubiquitylation K108 1.317 _GQDGIGSKAEK(gl)_
PARP1 Ubiquitylation K119 1.569 _TLGDFAAEYAK(gl)SNR_
PARP1 Ubiquitylation K131 1.025 1.620 _GCMEK(gl)IEK_
PARP1 Ubiquitylation K197 0.445 1.157 _K(gl)QLPGVK_
PARP1 Ubiquitylation K254 0.589 _AQNDLIWNIKDELKK(gl)_
PARP1 Ubiquitylation K262 0.456 _VCSTNDLK(gl)ELLIFNK_
PARP1 Ubiquitylation K320 1.464 1.034 _SDAYYCTGDVTAWTK(gl)CMVK_
PARP1 Ubiquitylation K331 -0.425 -0.480 _TQTPNRK(gl)EWVTPK_
PARP1 Ubiquitylation K337 0.462 0.332 _EWVTPK(gl)EFR_
PARP1 Ubiquitylation K346 0.370 0.411 _EISYLK(gl)K_
PARP1 Phosphorylation T368 -1.474 -1.410 _IFPPETSASVAAT(ph)PPPSTASAPAAVNSSASADKPLSNM(ox)K_
PARP1 Ubiquitylation K400 0.844 1.095 _ILTLGK(gl)LSR_
PARP1 Ubiquitylation K414 1.227 1.241 _AMIEK(gl)LGGK_
PARP1 Ubiquitylation K418 1.131 _LGGK(gl)LTGTANK_
PARP1 Ubiquitylation K425 0.912 0.815 _LTGTANK(gl)ASLCISTKK_
PARP1 Ubiquitylation K433 0.942 _ASLCISTK(gl)K_
PARP1 Ubiquitylation K434 0.020 _ASLCISTKK(gl)_
PARP1 Ubiquitylation K447 1.480 _MEEVK(gl)EANIR_
PARP1 Ubiquitylation K518 0.108 _GQVKEEGINK(gl)SEK_
PARP1 Ubiquitylation K521 0.630 _GQVKEEGINKSEK(gl)R_
PARP1 Ubiquitylation K548 0.125 -0.480 _GGAAVDPDSGLEHSAHVLEK(gl)GGK_
PARP1 Ubiquitylation K551 0.492 -0.573 _GGAAVDPDSGLEHSAHVLEKGGK(gl)_
PARP1 Ubiquitylation K629 1.632 _TGNAWHSK(gl)NFTK_
PARP1 Ubiquitylation K633 0.964 0.091 _NFTK(gl)YPK_
PARP1 Ubiquitylation K654 -0.086 _K(gl)LTVNPGTK_
PARP1 Ubiquitylation K662 0.112 _LTVNPGTK(gl)SK_
PARP1 Ubiquitylation K664 -0.042 -0.111 _LTVNPGTKSK(gl)_
PARP1 Ubiquitylation K683 0.983 1.355 _MIFDVESM(ox)K(gl)K_
PARP1 Ubiquitylation K684 1.213 1.355 _MIFDVESMKK(gl)_
PARP1 Ubiquitylation K700 0.448 _MPLGK(gl)LSK_
PARP1 Phosphorylation S782 0.648 0.490 _GGS(ph)DDSSKDPIDVNYEK_
PARP1 Ubiquitylation K949 0.738 _HSVK(gl)GLGK_
POLR3B Ubiquitylation K404 1.232 _AAQFDVVK(gl)HMR_
POLR3B Ubiquitylation K968 0.649 0.285 _FHYGTAFGGSK(gl)VK_
RABL6 Ubiquitylation K19 -0.391 _DK(gl)NIPAGLQSMNQALQR_
RABL6 Ubiquitylation K415 -0.417 _SFLEDTTPARDEKK(gl)_
RABL6 Phosphorylation S492 -0.342 _GPAPAPQQCS(ph)EPETK_
RABL6 Phosphorylation T599 -1.208 _RADDFPVRDDPSDVT(ph)DEDEGPAEPPPPPK_
RABL6 Phosphorylation S640 -0.181 _NDSDLFGLGLEEAGPKES(ph)SEEGKEGK_
RABL6 Phosphorylation S641 -0.181 _NDSDLFGLGLEEAGPKES(ph)SEEGKEGK_
RGS7 Phosphorylation S241 -1.071 -0.956 _SHS(ph)PTHTPTPETKPPTEDELQQQIK_
SCAPER Phosphorylation S86 0.674 _ITSSTTGDKHFDKS(ph)PTK_
SCAPER Phosphorylation S185 0.060 _HVIPS(ph)PSTDR_
SLC31A1 Ubiquitylation K96 -0.354 _K(gl)SQVSIR_
TAF2 Phosphorylation S1184 0.809 0.599 _EKDKEPFTFS(ph)SPASGR_
TAF2 Phosphorylation S1185 0.809 _EKDKEPFTFS(ph)SPASGR_
TRMT1 Ubiquitylation K283 0.868 0.731 _YGAMALK(gl)SR_
TRMT1 Ubiquitylation K483 -0.399 _VSLSHACK(gl)NAVK_
TRMT1 Phosphorylation S623 -0.536 _GDQCCYS(ph)HSPPTPR_
TRMT1 Phosphorylation S625 -0.651 -0.411 _GDQCCYSHS(ph)PPTPR_
UBR7 Ubiquitylation K292 -0.820 _LQELK(gl)AK_
UBR7 Ubiquitylation K346 0.130 _GK(gl)IAQATDR_
UBR7 Ubiquitylation K384 1.341 _TELK(gl)DYLKR_
UBR7 Ubiquitylation K398 1.110 0.300 _FADEGTVVK(gl)R_
UBR7 Ubiquitylation K413 0.174 _EDIQQFFEEFQSKK(gl)_
WDR45B Ubiquitylation K206 0.484 _IATASEK(gl)GTLIR_
WDR45B Ubiquitylation K266 -0.455 _NK(gl)QSSLASASFLPK_
ZBTB40 Phosphorylation S214 -0.546 _NAETPAETPTTAEACS(ph)PSPAVQTFSEAK_
ZCCHC8 Phosphorylation T479 -0.884 -1.081 _GT(ph)PPPVFT(ph)PPLPK_
ZCCHC8 Phosphorylation T485 -2.305 _GT(ph)PPPVFT(ph)PPLPK_
ZCCHC8 Phosphorylation S597 0.616 0.863 _SEAGHAS(ph)SPDSEVTSLCQK_
ZCCHC8 Phosphorylation S598 0.975 1.077 _SEAGHASS(ph)PDSEVTSLCQK_
ZCCHC8 Phosphorylation S649 0.158 -0.490 _LFPADTS(ph)PSTATK_
ZCCHC8 Phosphorylation S658 0.694 _IHS(ph)PIPDMSK_


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