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Query: ERLIN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ERLIN2 0 1.458 0.000 -0.170 0.649 0.355

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ERLIN2 Ubiquitylation K190 0.454 _NYELMESEK(gl)TK_
ERLIN2 Ubiquitylation K192 -0.074 _TK(gl)LLIAAQK_
ERLIN2 Ubiquitylation K199 -0.112 _LLIAAQK(gl)QK_
ERLIN2 Ubiquitylation K201 -0.188 _LLIAAQKQK(gl)_

Background Information for ERLIN2:





Protein-protein Interactions for ERLIN2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM82A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait KLHL21 Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCSTN Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait UFL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait ERLIN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF170 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMUB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ERLIN2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Band_7 IPR001107 0


Protein complexes (CORUM database) featuring ERLIN2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ERLIN2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0030433 ER-associated ubiquitin-dependent protein catabolic process Database 0.33
Category members Disease phenotype Juvenile_primary_lateral_sclerosis Juvenile primary lateral sclerosis Database 0.11
Category members GO Category GO:0008219 cell death Database 0.08
Category members Disease phenotype Autosomal_Recessive_Mental_Retardation Autosomal Recessive Mental Retardation Database 0


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