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Query: EEF1B2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EEF1B2 2 6.714 1.060 -0.810 -0.092 0.144 -0.187 -0.001 0.028
EEF1B2 2 6.714 1.400 -0.530 -0.092 0.144 -0.187 -0.001 0.028

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EEF1B2 Ubiquitylation K186 2.509 4.473 _LVPVGYGIKK(gl)_
EEF1B2 Phosphorylation S106 -0.152 -0.007 _YGPADVEDTTGSGATDSKDDDDIDLFGS(ph)DDEEESEEAKR_

Background Information for EEF1B2:


Pubmed-EEF1B2 »
Uniprot-EEF1B2 »
Biogrid-EEF1B2 »
ProteomicsDB-EEF1B2 »

Tumorportal-EEF1B2 »
COSMIC-EEF1B2 »
GenomeRNAi-EEF1B2 »
Genecards-EEF1B2


Protein-protein Interactions for EEF1B2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EEF1A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EEF1D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EEF1G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLLT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EEF1B2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glutathione-S-Trfase_C-like IPR010987 0.23
Category members Transl_elong_fac_EF1B_bsu/dsu IPR014038 0.04
Category members EF-1_beta_acid_region_euk IPR018940 0.04


Protein complexes (CORUM database) featuring EEF1B2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EEF1B2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005853 eukaryotic translation elongation factor 1 complex Database 0.6
Category members GO Category GO:0003746 translation elongation factor activity Database 0.08
Category members Disease phenotype Autosomal_Recessive_Mental_Retardation Autosomal Recessive Mental Retardation Database 0


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