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Query: TRMT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRMT1 0 -0.037 -0.640 0.800 -1.192
TRMT1 0 -0.037 -0.640 0.800 -0.296

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRMT1 Ubiquitylation K283 0.868 0.731 _YGAMALK(gl)SR_
TRMT1 Phosphorylation S625 -0.651 -0.411 _GDQCCYSHS(ph)PPTPR_
TRMT1 Ubiquitylation K483 -0.399 _VSLSHACK(gl)NAVK_
TRMT1 Phosphorylation S623 -0.536 _GDQCCYS(ph)HSPPTPR_

Background Information for TRMT1:


Pubmed-TRMT1 »
Uniprot-TRMT1 »
Biogrid-TRMT1 »
ProteomicsDB-TRMT1 »

Tumorportal-TRMT1 »
COSMIC-TRMT1 »
GenomeRNAi-TRMT1 »
Genecards-TRMT1


Protein-protein Interactions for TRMT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LIPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RFPL4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDYHV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRMT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members tRNA_Trfase_Trm5/Tyw2 IPR003402 0.61
Category members Trm1 IPR002905 0.24
Category members SAM-dependent_MTases-like IPR029063 0.04
Category members Znf_CCCH IPR000571 0.03


Protein complexes (CORUM database) featuring TRMT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TRMT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0008033 tRNA processing Database 0.39
Category members GO Category GO:0004809 tRNA (guanine-N2-)-methyltransferase activity Database 0.24
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members Disease phenotype Autosomal_Recessive_Mental_Retardation Autosomal Recessive Mental Retardation Database 0
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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