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Query: RGS7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RGS7 0 -2.027 0.820 -0.610

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RGS7 Phosphorylation S241 -1.071 -0.956 _SHS(ph)PTHTPTPETKPPTEDELQQQIK_

Background Information for RGS7:


Pubmed-RGS7 »
Uniprot-RGS7 »
Biogrid-RGS7 »
ProteomicsDB-RGS7 »

Tumorportal-RGS7 »
COSMIC-RGS7 »
GenomeRNAi-RGS7 »
Genecards-RGS7


Protein-protein Interactions for RGS7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GNB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RGS7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DEP_dom IPR000591 0.07
Category members Regulat_G_prot_signal_superfam IPR016137 0.05
Category members RGS_dom IPR000342 0
Category members G-protein_gamma-like_dom IPR015898 0


Protein complexes (CORUM database) featuring RGS7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RGS7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members Pathway Pathway_263 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 0 0.49
Category members GO Category GO:0043547 positive regulation of GTPase activity Database 0.21
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0038032 termination of G-protein coupled receptor signaling pathway Database 0.05
Category members GO Category GO:0031681 G-protein beta-subunit binding Database 0.04
Category members Disease phenotype Autosomal_Recessive_Mental_Retardation Autosomal Recessive Mental Retardation Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0005834 heterotrimeric G-protein complex Database 0
Category members GO Category GO:0008277 regulation of G-protein coupled receptor protein signaling pathway Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0044292 dendrite terminus Database 0


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