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Query: MAN1B1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAN1B1 0 0.407 -1.220 1.640

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAN1B1 Ubiquitylation K562 -1.233 _DVEVK(gl)PADR_

Background Information for MAN1B1:


Pubmed-MAN1B1 »
Uniprot-MAN1B1 »
Biogrid-MAN1B1 »
ProteomicsDB-MAN1B1 »

Tumorportal-MAN1B1 »
COSMIC-MAN1B1 »
GenomeRNAi-MAN1B1 »
Genecards-MAN1B1


Protein-protein Interactions for MAN1B1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNDBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RANBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAN1B1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_hydro_47 IPR001382 0.04


Protein complexes (CORUM database) featuring MAN1B1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAN1B1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006457 protein folding Database 4.93
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0030433 ER-associated ubiquitin-dependent protein catabolic process Database 0.33
Category members GO Category GO:0009311 oligosaccharide metabolic process Database 0.17
Category members GO Category GO:0044322 endoplasmic reticulum quality control compartment Database 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Database 0.06
Category members Pathway Pathway_109 KEGG_N_GLYCAN_BIOSYNTHESIS 0 0.04
Category members Pathway Pathway_464 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE 0 0
Category members Pathway Pathway_465 REACTOME_CALNEXIN_CALRETICULIN_CYCLE 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members Disease phenotype Autosomal_Recessive_Mental_Retardation Autosomal Recessive Mental Retardation Database 0
Category members Disease phenotype Autosomal_recessive_non-syndromic_intellectual_disability Autosomal recessive non-syndromic intellectual disability Database 0
Category members GO Category GO:0006487 protein N-linked glycosylation Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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