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Autosomal recessive non-syndromic intellectual disability
(Autosomal_recessive_non-syndromic_intellectual_disability)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
NSUN2 1 -0.630 0.380 0.495 -0.365
NSUN2 1 -0.630 0.380 -0.793 -0.402 -0.165
MED23 1 0.740 -0.420 0.242 1.739 -1.089 0.014
TECR 0 0.220 -0.260 0.497 0.272
ZC3H14 0 -0.430 0.230 -0.064 -0.354 -0.005
TUSC3 0 0.700 -0.570
CRBN 0 0.460 -0.110
MED13L 0 -0.540 0.950
CC2D1A 0 0.350 -0.860 -0.479 0.221
KIAA1033 0 -1.300 1.490
MAN1B1 0 -1.220 1.640

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CC2D1A Phosphorylation T120 -2.527 -2.190 _ASET(ph)PPPVAQPKPEAPHPGLETTLQER_
CC2D1A Phosphorylation T204 -1.886 _GPAST(ph)PTYS(ph)PAPTQPAPR_
CC2D1A Phosphorylation S208 -1.886 _GPAST(ph)PTYS(ph)PAPTQPAPR_
CC2D1A Phosphorylation S455 -0.744 -0.266 _KQNS(ph)PVAPTAQPK_
CRBN Phosphorylation S25 -0.511 _(ac)AGEGDQQDAAHNMGNHLPLLPAES(ph)EEEDEMEVEDQDSK_
CRBN Ubiquitylation K116 -0.048 0.253 _NLIQK(gl)DR_
CRBN Ubiquitylation K166 -0.610 _FK(gl)VLELR_
CRBN Ubiquitylation K300 -0.793 0.781 _IQLLK(gl)IGSAIQR_
KIAA1033 Ubiquitylation K1090 0.668 -0.322 _AVAK(gl)QQNVQSASQDEK_
MAN1B1 Ubiquitylation K562 -1.233 _DVEVK(gl)PADR_
MED13L Phosphorylation S817 -0.258 _AGSSSLTQVTDLAPSLHDLDNIFDNS(ph)DDDELGAVSPALR_
MED13L Phosphorylation S923 0.430 0.314 _MEVEDGLGS(ph)PKPEEIKDFSYVHK_
MED23 Ubiquitylation K471 -1.404 _NK(gl)SLQMNDYK_
MED23 Ubiquitylation K679 -0.706 _FLSDPK(gl)TVLSAESEELNR_
MED23 Ubiquitylation K1088 -0.793 _LVDTMAGK(gl)SPGPFPNCDWR_
NSUN2 Ubiquitylation K95 0.374 _EILHCLK(gl)NK_
NSUN2 Ubiquitylation K229 1.125 _CYLLVHQAK(gl)R_
NSUN2 Ubiquitylation K286 0.469 -0.479 _NIDVWKK(gl)_
NSUN2 Ubiquitylation K437 -0.886 _SSMPWNK(gl)R_
NSUN2 Phosphorylation T453 0.154 0.148 _EST(ph)QLSPADLTEGKPTDPSK_
NSUN2 Phosphorylation S456 0.187 0.131 _ESTQLS(ph)PADLTEGKPTDPSK_
NSUN2 Ubiquitylation K565 1.464 _QLYMVSK(gl)ELR_
NSUN2 Ubiquitylation K577 0.039 _NVLLNNSEK(gl)MK_
NSUN2 Ubiquitylation K579 1.054 -0.390 _MK(gl)VINTGIK_
NSUN2 Phosphorylation S593 1.207 1.722 _NNS(ph)GEEFDCAFR_
NSUN2 Ubiquitylation K640 0.276 -0.635 _K(gl)LSSETYSQAK_
NSUN2 Ubiquitylation K650 0.357 -0.742 _KLSSETYSQAK(gl)DLAK_
NSUN2 Ubiquitylation K654 0.538 -0.353 _DLAK(gl)GSIVLK_
NSUN2 Phosphorylation S743 -1.676 -1.545 _AGEPNS(ph)PDAEEANS(ph)PDVTAGCDPAGVHPPR_
NSUN2 Phosphorylation S751 -0.991 -1.534 _AGEPNSPDAEEANS(ph)PDVTAGCDPAGVHPPR_
TECR Ubiquitylation K12 -0.345 _HYEVEILDAK(gl)TR_
TECR Ubiquitylation K224 -0.509 _DLRPAGSK(gl)TR_
TECR Ubiquitylation K291 -0.791 -0.675 _SYLK(gl)EFRDYPPLR_
TUSC3 Ubiquitylation K72 -0.120 _MNGDK(gl)FR_
TUSC3 Ubiquitylation K78 -0.759 _FIK(gl)APPR_
ZC3H14 Phosphorylation S268 1.200 _LCEPEVLNS(ph)LEETYSPFFR_
ZC3H14 Phosphorylation S343 0.611 -0.107 _RPS(ph)LPPSK_
ZC3H14 Phosphorylation S409 0.071 0.063 _IS(ph)PPIKEEETKGDSVEK_
ZC3H14 Ubiquitylation K470 0.672 _SFILK(gl)KPK_
ZC3H14 Ubiquitylation K489 0.279 _LSEEVVVAPNQESGMK(gl)TADSLR_
ZC3H14 Phosphorylation S515 -0.151 -0.176 _DLVQPDKPAS(ph)PK_
ZC3H14 Phosphorylation S620 -0.185 -0.265 _NGDECAYHHPIS(ph)PCK_
ZC3H14 Phosphorylation S665 0.039 _RIPVLS(ph)PK_


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