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Query: MED13L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MED13L 0 1.694 -0.540 0.950

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MED13L Phosphorylation S923 0.430 0.314 _MEVEDGLGS(ph)PKPEEIKDFSYVHK_
MED13L Phosphorylation S817 -0.258 _AGSSSLTQVTDLAPSLHDLDNIFDNS(ph)DDDELGAVSPALR_

Background Information for MED13L:


Pubmed-MED13L »
Uniprot-MED13L »
Biogrid-MED13L »
ProteomicsDB-MED13L »

Tumorportal-MED13L »
COSMIC-MED13L »
GenomeRNAi-MED13L »
Genecards-MED13L


Protein-protein Interactions for MED13L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK8 Cat. description Hein, Mann, Cell 2015
Category members IP bait MED12 Cat. description Hein, Mann, Cell 2015
Category members IP bait MED22 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MED13L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cystine-knot_cytokine IPR029034 0.52
Category members Mediator_Med13 IPR009401 0.04
Category members Mediator_Med13_N_met/fun IPR021643 0.04


Protein complexes (CORUM database) featuring MED13L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 230 Mediator complex Database 0.76
Category members Corum 5450 Mediator complex Database 0.45


Categories featuring MED13L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0016592 mediator complex Database 0.53
Category members Pathway Pathway_41 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 0 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0001104 RNA polymerase II transcription cofactor activity Database 0.08
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Disease phenotype Autosomal_recessive_non-syndromic_intellectual_disability Autosomal recessive non-syndromic intellectual disability Database 0
Category members Disease phenotype Congenitally_uncorrected_transposition_of_the_great_arteries Congenitally uncorrected transposition of the great arteries Database 0


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