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Query: AMPD2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AMPD2 1 1.320 2.140 -1.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AMPD2 Phosphorylation S76 0.719 _RAS(ph)LQASTAAPEAR_
AMPD2 Phosphorylation S168 0.601 0.268 _QIS(ph)QDVKLEPDILLR_
AMPD2 Phosphorylation S100 0.448 -0.155 _S(ph)LPGPAPCLK_

Background Information for AMPD2:


Pubmed-AMPD2 »
Uniprot-AMPD2 »
Biogrid-AMPD2 »
ProteomicsDB-AMPD2 »

Tumorportal-AMPD2 »
COSMIC-AMPD2 »
GenomeRNAi-AMPD2 »
Genecards-AMPD2


Protein-protein Interactions for AMPD2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C14orf105 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPBP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AMPD2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members A/AMP_deaminase_dom IPR001365 0
Category members AMPD IPR006329 0


Protein complexes (CORUM database) featuring AMPD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AMPD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members Pathway Pathway_205 REACTOME_PURINE_SALVAGE 0 0
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members GO Category GO:0003876 AMP deaminase activity Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0006163 purine nucleotide metabolic process Database 0
Category members GO Category GO:0006188 IMP biosynthetic process Database 0
Category members GO Category GO:0019239 deaminase activity Database 0
Category members GO Category GO:0032264 IMP salvage Database 0
Category members GO Category GO:0043101 purine-containing compound salvage Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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