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Query: ADSL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADSL 0 0.018 0.990 -0.600
ADSL 0 0.018 0.990 -0.600 -0.508 0.257 -0.090

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADSL Phosphorylation S9 0.246 0.261 _(ac)AAGGDHGS(ph)PDSYR_
ADSL Ubiquitylation K429 -0.148 _VLSQQAASVVK(gl)QEGGDNDLIER_
ADSL Ubiquitylation K243 -0.448 _MVTEK(gl)AGFKR_
ADSL Ubiquitylation K309 -1.057 _QQIGSSAMPYK(gl)R_

Background Information for ADSL:


Pubmed-ADSL »
Uniprot-ADSL »
Biogrid-ADSL »
ProteomicsDB-ADSL »

Tumorportal-ADSL »
COSMIC-ADSL »
GenomeRNAi-ADSL »
Genecards-ADSL


Protein-protein Interactions for ADSL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEKT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEKT4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ADSL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members L-Aspartase-like IPR008948 0.04
Category members Fumarate_lyase_fam IPR000362 0
Category members Fumarate_lyase_N IPR022761 0


Protein complexes (CORUM database) featuring ADSL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ADSL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051262 protein tetramerization Database 0.6
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_273 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS 0 0.23
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members GO Category GO:0006189 'de novo' IMP biosynthetic process Database 0.13
Category members GO Category GO:0009168 purine ribonucleoside monophosphate biosynthetic process Database 0.12
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members GO Category GO:0009060 aerobic respiration Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_272 KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 0 0.04
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0006163 purine nucleotide metabolic process Database 0
Category members GO Category GO:0006164 purine nucleotide biosynthetic process Database 0
Category members GO Category GO:0006167 AMP biosynthetic process Database 0
Category members GO Category GO:0007584 response to nutrient Database 0
Category members GO Category GO:0009156 ribonucleoside monophosphate biosynthetic process Database 0
Category members GO Category GO:0014850 response to muscle activity Database 0
Category members GO Category GO:0042594 response to starvation Database 0
Category members GO Category GO:0044208 'de novo' AMP biosynthetic process Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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