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Query: GAS6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GAS6 0 0.220 0.020 0.220 -1.517 -0.502

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for GAS6:


Pubmed-GAS6 »
Uniprot-GAS6 »
Biogrid-GAS6 »
ProteomicsDB-GAS6 »

Tumorportal-GAS6 »
COSMIC-GAS6 »
GenomeRNAi-GAS6 »
Genecards-GAS6


Protein-protein Interactions for GAS6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAM32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP1B4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC12A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GALNT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPPE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NTNG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHB16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTBDN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMED6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GAS6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EG-like_dom IPR000742 1.74
Category members EGF-like_Ca-bd_dom IPR001881 0.69
Category members GLA_domain IPR000294 0.28
Category members Laminin_G IPR001791 0.06
Category members ConA-like_lec_gl_sf IPR008985 0


Protein complexes (CORUM database) featuring GAS6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GAS6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0070374 positive regulation of ERK1 and ERK2 cascade Database 0.65
Category members GO Category GO:0005796 Golgi lumen Database 0.64
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0070588 calcium ion transmembrane transport Database 0.25
Category members GO Category GO:0032689 negative regulation of interferon-gamma production Database 0.25
Category members GO Category GO:0001934 positive regulation of protein phosphorylation Database 0.22
Category members GO Category GO:0019079 viral genome replication Database 0.22
Category members GO Category GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity Database 0.18
Category members GO Category GO:0018105 peptidyl-serine phosphorylation Database 0.18
Category members GO Category GO:0017187 peptidyl-glutamic acid carboxylation Database 0.13
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0035690 cellular response to drug Database 0.1
Category members GO Category GO:0006909 phagocytosis Database 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0045860 positive regulation of protein kinase activity Database 0.06
Category members GO Category GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Database 0.05
Category members GO Category GO:0048146 positive regulation of fibroblast proliferation Database 0.05
Category members GO Category GO:0070527 platelet aggregation Database 0.05
Category members GO Category GO:0046718 viral entry into host cell Database 0.04
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0061098 positive regulation of protein tyrosine kinase activity Database 0.04
Category members GO Category GO:0035754 B cell chemotaxis Database 0.04
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members GO Category GO:0031589 cell-substrate adhesion Database 0.04
Category members GO Category GO:0009267 cellular response to starvation Database 0.03
Category members GO Category GO:0033138 positive regulation of peptidyl-serine phosphorylation Database 0.03
Category members GO Category GO:0046827 positive regulation of protein export from nucleus Database 0.03
Category members GO Category GO:0032715 negative regulation of interleukin-6 production Database 0.03
Category members GO Category GO:0031100 organ regeneration Database 0.01
Category members GO Category GO:0032825 positive regulation of natural killer cell differentiation Database 0.01
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0001786 phosphatidylserine binding Database 0
Category members GO Category GO:0001961 positive regulation of cytokine-mediated signaling pathway Database 0
Category members GO Category GO:0002576 platelet degranulation Database 0
Category members GO Category GO:0003104 positive regulation of glomerular filtration Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005245 voltage-gated calcium channel activity Database 0
Category members GO Category GO:0005788 endoplasmic reticulum lumen Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007167 enzyme linked receptor protein signaling pathway Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0019064 fusion of virus membrane with host plasma membrane Database 0
Category members GO Category GO:0030296 protein tyrosine kinase activator activity Database 0
Category members GO Category GO:0030971 receptor tyrosine kinase binding Database 0
Category members GO Category GO:0031093 platelet alpha granule lumen Database 0
Category members GO Category GO:0032008 positive regulation of TOR signaling Database 0
Category members GO Category GO:0032148 activation of protein kinase B activity Database 0
Category members GO Category GO:0032720 negative regulation of tumor necrosis factor production Database 0
Category members GO Category GO:0033159 negative regulation of protein import into nucleus, translocation Database 0
Category members GO Category GO:0035457 cellular response to interferon-alpha Database 0
Category members GO Category GO:0040008 regulation of growth Database 0
Category members GO Category GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0043277 apoptotic cell clearance Database 0
Category members GO Category GO:0043491 protein kinase B signaling Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0046813 receptor-mediated virion attachment to host cell Database 0
Category members GO Category GO:0048018 receptor agonist activity Database 0
Category members GO Category GO:0050711 negative regulation of interleukin-1 secretion Database 0
Category members GO Category GO:0050766 positive regulation of phagocytosis Database 0
Category members GO Category GO:0051897 positive regulation of protein kinase B signaling Database 0
Category members GO Category GO:0060090 binding, bridging Database 0
Category members GO Category GO:0070168 negative regulation of biomineral tissue development Database 0
Category members GO Category GO:0071333 cellular response to glucose stimulus Database 0
Category members GO Category GO:0071363 cellular response to growth factor stimulus Database 0


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