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negative regulation of interleukin-6 production
(GO:0032715)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ARRB2 1 2.000 -1.160 -0.340 0.096 0.051 -1.604
GBA 1 -1.380 2.580 0.407 0.357 0.150
TNFRSF1A 0 -0.590 0.470
CSK 0 1.200 -0.960 -1.211
CSK 0 1.200 -0.960
TNFAIP3 0 0.760 -0.500
VIMP 0 0.490 -0.510 -2.036
ARRB1 0 0.960 -0.620
NLRX1 0 -0.720 0.810 -0.012
GAS6 0 0.020 0.220 -1.517 -0.502

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ARRB1 Phosphorylation S412 0.138 0.253 _GMKDDKEEEEDGTGS(ph)PQLNNR_
ARRB2 Ubiquitylation K199 -1.933 _VQFAPEK(gl)PGPQPSAETTR_
CSK Ubiquitylation K196 -0.133 _SGWALNMKELK(gl)_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
TNFRSF1A Ubiquitylation K242 -0.111 _SK(gl)LYSIVCGK_
VIMP Ubiquitylation K117 -2.952 -1.705 _AAAAVEPDVVVK(gl)R_
VIMP Ubiquitylation K190 -1.565 -1.157 _KPQEEDSPGPSTSSVLK(gl)R_


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