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Query: NLRX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NLRX1 0 0.798 -0.720 0.810 -0.012

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for NLRX1:


Pubmed-NLRX1 »
Uniprot-NLRX1 »
Biogrid-NLRX1 »
ProteomicsDB-NLRX1 »

Tumorportal-NLRX1 »
COSMIC-NLRX1 »
GenomeRNAi-NLRX1 »
Genecards-NLRX1


Protein-protein Interactions for NLRX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CREB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NLGN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NLRX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NLRX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members NACHT_NTPase IPR007111 0.23
Category members Leu-rich_rpt_RNase_inh_sub-typ IPR003590 0.06


Protein complexes (CORUM database) featuring NLRX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NLRX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members Pathway Pathway_484 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 0 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0032715 negative regulation of interleukin-6 production Database 0.03
Category members Pathway Pathway_483 KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_785 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING 0 0
Category members GO Category GO:0032480 negative regulation of type I interferon production Database 0
Category members GO Category GO:0032688 negative regulation of interferon-beta production Database 0
Category members GO Category GO:0039536 negative regulation of RIG-I signaling pathway Database 0
Category members GO Category GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0045824 negative regulation of innate immune response Database 0
Category members GO Category GO:0050728 negative regulation of inflammatory response Database 0


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