bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Category

Results for the Category
negative regulation of type I interferon production
(GO:0032480)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPS27A 4 -1.330 2.560 -0.309 0.131 -0.009
UBC 3 -0.309 0.131 -0.009
UBC 3
UBC 3
UBB 3 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180
ITCH 1 1.000 -0.610 -0.346 0.023 0.613
TRIM25 1 -0.120 -0.240 0.224 -1.159
CYLD 0 -1.250 2.010
MAVS 0 1.610 -0.380 -1.056 -0.630
RNF125 0 0.020 0.450
UBE2D3 0 -1.120 1.910 -0.582 -0.725 -0.315
IFIH1 0 1.630 -0.790
TNFAIP3 0 0.760 -0.500
IRF3 0 -0.190 -0.050
PIN1 0 -0.060 -0.440 -1.204 -0.594
TRAF3 0 -1.050 1.040
HERC5 0 -0.330 1.710
IKBKE 0
TBK1 0
ATG12 0 -0.150 1.370
NLRX1 0 -0.720 0.810 -0.012
PCBP2 0 -0.130 -0.320
PCBP2 0 -0.130 -0.320
PCBP2 0 -0.130 -0.320 -0.835 -0.602 -0.993 -0.725 -0.337

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATG12 Ubiquitylation K116 0.431 _AVGDTPIMK(gl)TK_
ATG12 Ubiquitylation K118 0.431 _AVGDTPIMK(gl)TK_
CYLD Ubiquitylation K114 -1.068 0.927 _FSLFK(gl)NR_
HERC5 Ubiquitylation K397 -3.968 _TIPTLNEGTVK(gl)R_
HERC5 Ubiquitylation K406 -1.155 _WIADVETK(gl)R_
IFIH1 Phosphorylation S301 -1.067 _AS(ph)PEPELQLRPYQMEVAQPALEGK_
IKBKE Ubiquitylation K137 -0.689 _DIK(gl)PGNIMR_
IRF3 Phosphorylation S173 -0.663 -1.111 _S(ph)PSLDNPTPFPNLGPSENPLK_
IRF3 Phosphorylation S175 -0.663 -0.661 _S(ph)PSLDNPTPFPNLGPSENPLKR_
IRF3 Ubiquitylation K193 -3.309 -3.157 _SPSLDNPTPFPNLGPSENPLK(gl)R_
ITCH Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
ITCH Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
ITCH Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
ITCH Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_
ITCH Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
ITCH Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_
MAVS Phosphorylation S152 0.146 -0.466 _EKEPSYPMPVQETQAPES(ph)PGENSEQALQTLSPR_
MAVS Phosphorylation S165 -0.888 _EKEPSYPMPVQETQAPESPGENSEQALQTLS(ph)PR_
MAVS Phosphorylation S222 1.349 1.006 _GPVS(ph)PSVSFQPLAR_
MAVS Ubiquitylation K362 0.082 _AGMVPSK(gl)VPTSMVLTK_
PCBP2 Ubiquitylation K35 0.116 _LLMHGK(gl)EVGSIIGK_
PCBP2 Ubiquitylation K43 -0.219 _EVGSIIGK(gl)KGESVK_
PCBP2 Ubiquitylation K44 0.838 0.772 _EVGSIIGKK(gl)_
PCBP2 Ubiquitylation K127 -0.025 -0.311 _LVVPASQCGSLIGK(gl)GGCK_
PCBP2 Phosphorylation Y182 -0.851 _GVTIPY(ph)RPKPSSSPVIFAGGQDR_
PCBP2 Phosphorylation S187 -1.067 -0.515 _PS(ph)SSPVIFAGGQDR_
PCBP2 Phosphorylation S188 -0.453 -0.085 _PSS(ph)SPVIFAGGQDR_
PCBP2 Phosphorylation S189 -0.396 _PSSS(ph)PVIFAGGQLTK_
PCBP2 Phosphorylation S189 -0.991 -0.649 _PKPSSS(ph)PVIFAGGQDR_
PCBP2 Phosphorylation S272 -0.207 -0.267 _LHQLAM(ox)QQSHFPM(ox)THGNTGFSGIESSS(ph)PEVK_
PCBP2 Ubiquitylation K317 0.274 0.191 _QGAK(gl)INEIR_
PCBP2 Ubiquitylation K330 -0.123 0.488 _QM(ox)SGAQIK(gl)IANPVEGSTDR_
PIN1 Ubiquitylation K13 -0.216 -0.516 _(ac)ADEEKLPPGWEK(gl)R_
PIN1 Ubiquitylation K117 0.117 _SGEEDFESLASQFSDCSSAK(gl)AR_
RNF125 Ubiquitylation K66 -0.518 _SCIATSLK(gl)NNK_
RNF125 Ubiquitylation K69 -0.518 _SCIATSLK(gl)NNK_
RNF125 Ubiquitylation K91 -0.097 _AYLPSEGVPATDVAK(gl)R_
RPS27A Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
RPS27A Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
RPS27A Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
RPS27A Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
RPS27A Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
RPS27A Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
RPS27A Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
RPS27A Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
RPS27A Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
RPS27A Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
TBK1 Ubiquitylation K137 -0.689 _DIK(gl)PGNIMR_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
TRAF3 Ubiquitylation K369 -1.061 -2.137 _VTELESVDK(gl)SAGQVAR_
TRIM25 Phosphorylation S114 -0.310 -0.309 _ASAPS(ph)PNAQVACDHCLK_
TRIM25 Ubiquitylation K453 1.749 _AK(gl)VLETFLAK_
UBA52 Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBA52 Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBA52 Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBA52 Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBA52 Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBA52 Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBA52 Ubiquitylation K93 0.181 2.418 _YNCDK(gl)MICR_
UBA52 Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBA52 Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBA52 Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBA52 Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBB Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBB Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBB Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBB Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBB Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBB Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBB Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBB Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBB Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBB Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBC Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBC Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBC Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBC Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBC Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBC Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBC Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBC Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBC Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBE2D3 Ubiquitylation K8 0.326 _INK(gl)ELSDLAR_
UBE2D3 Ubiquitylation K101 -0.229 _SQWSPALTISK(gl)_
UBE2D3 Ubiquitylation K128 0.754 _IYK(gl)TDRDK(gl)YNR_
UBE2D3 Ubiquitylation K133 0.005 _IYK(gl)TDRDK(gl)YNR_
UBE2D3 Ubiquitylation K144 0.212 0.074 _EWTQK(gl)YAM_


.

© Copyright Svejstrup Laboratory 2015