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Query: PCBP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PCBP2 0 -0.579 -0.130 -0.320
PCBP2 0 -0.579 -0.130 -0.320 -0.835 -0.602 -0.993 -0.725 -0.337

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PCBP2 Ubiquitylation K44 0.838 0.772 _EVGSIIGKK(gl)_
PCBP2 Ubiquitylation K330 -0.123 0.488 _QM(ox)SGAQIK(gl)IANPVEGSTDR_
PCBP2 Ubiquitylation K317 0.274 0.191 _QGAK(gl)INEIR_
PCBP2 Phosphorylation S188 -0.453 -0.085 _PSS(ph)SPVIFAGGQDR_
PCBP2 Ubiquitylation K43 -0.219 _EVGSIIGK(gl)KGESVK_
PCBP2 Phosphorylation S272 -0.207 -0.267 _LHQLAM(ox)QQSHFPM(ox)THGNTGFSGIESSS(ph)PEVK_
PCBP2 Ubiquitylation K127 -0.025 -0.311 _LVVPASQCGSLIGK(gl)GGCK_
PCBP2 Phosphorylation S189 -0.396 _PSSS(ph)PVIFAGGQLTK_
PCBP2 Phosphorylation S187 -1.067 -0.515 _PS(ph)SSPVIFAGGQDR_
PCBP2 Phosphorylation S189 -0.991 -0.649 _PKPSSS(ph)PVIFAGGQDR_
PCBP2 Phosphorylation Y182 -0.851 _GVTIPY(ph)RPKPSSSPVIFAGGQDR_
PCBP2 Ubiquitylation K35 0.116 _LLMHGK(gl)EVGSIIGK_

Background Information for PCBP2:


Pubmed-PCBP2 »
Uniprot-PCBP2 »
Biogrid-PCBP2 »
ProteomicsDB-PCBP2 »

Tumorportal-PCBP2 »
COSMIC-PCBP2 »
GenomeRNAi-PCBP2 »
Genecards-PCBP2


Protein-protein Interactions for PCBP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKRD26 Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait PCBP2 Cat. description Hein, Mann, Cell 2015


Protein Domains in PCBP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members KH_dom_type_2 IPR004044 0.34
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13


Protein complexes (CORUM database) featuring PCBP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PCBP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members Pathway Pathway_484 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 0 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0050687 negative regulation of defense response to virus Database 0.03
Category members Pathway Pathway_785 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING 0 0
Category members GO Category GO:0032480 negative regulation of type I interferon production Database 0


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