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Query: ATG12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ATG12 0 1.801 -0.150 1.370

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ATG12 Ubiquitylation K116 0.431 _AVGDTPIMK(gl)TK_
ATG12 Ubiquitylation K118 0.431 _AVGDTPIMK(gl)TK_

Background Information for ATG12:


Pubmed-ATG12 »
Uniprot-ATG12 »
Biogrid-ATG12 »
ProteomicsDB-ATG12 »

Tumorportal-ATG12 »
COSMIC-ATG12 »
GenomeRNAi-ATG12 »
Genecards-ATG12


Protein-protein Interactions for ATG12
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATG10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ATG12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Atg8_like IPR004241 0
Category members Atg12 IPR007242 0


Protein complexes (CORUM database) featuring ATG12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ATG12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members Pathway Pathway_484 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 0 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_483 KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_526 KEGG_REGULATION_OF_AUTOPHAGY 0 0
Category members Pathway Pathway_785 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING 0 0
Category members GO Category GO:0000045 autophagic vacuole assembly Database 0
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0032480 negative regulation of type I interferon production Database 0
Category members GO Category GO:0034045 pre-autophagosomal structure membrane Database 0


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