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Query: RNF125

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNF125 0 0.353 0.020 0.450

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNF125 Ubiquitylation K91 -0.097 _AYLPSEGVPATDVAK(gl)R_
RNF125 Ubiquitylation K66 -0.518 _SCIATSLK(gl)NNK_
RNF125 Ubiquitylation K69 -0.518 _SCIATSLK(gl)NNK_

Background Information for RNF125:


Pubmed-RNF125 »
Uniprot-RNF125 »
Biogrid-RNF125 »
ProteomicsDB-RNF125 »

Tumorportal-RNF125 »
COSMIC-RNF125 »
GenomeRNAi-RNF125 »
Genecards-RNF125


Protein-protein Interactions for RNF125
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in RNF125
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring RNF125
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RNF125
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members Pathway Pathway_484 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 0 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_483 KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_785 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING 0 0
Category members GO Category GO:0032480 negative regulation of type I interferon production Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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