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Results for the Category
negative regulation of sequence-specific DNA binding transcription factor activity
(GO:0043433)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PBX2 2 -0.170 0.670 -0.186 -0.124
KDM1A 1 -1.020 1.190 1.814 0.225
KDM1A 1 -1.020 1.190 0.355 0.031 0.593
KAT6A 1 0.100 -0.500 0.334 0.461
PEX14 1 -1.140 1.100 -0.395 0.423
HDAC2 1 -2.390 4.970
HDAC2 1 -2.390 4.970 0.187 -0.007 0.825
HDAC4 0 1.730 -0.740
SIRT1 0 0.910 -0.910
HMOX1 0 0.330 0.220 -1.817 -1.289
SUFU 0 1.190 -0.990
WFS1 0 -0.390 0.420 -0.793 -0.234
ID2 0 -0.080 -0.630
SUMO1 0 0.450 0.060 -0.088 0.599 0.276 0.608 0.499
MAD2L2 0 -0.960 1.170
PROX1 0 0.800 -0.550
TWIST1 0 -0.640 1.150
RLIM 0 1.810 -0.920 -0.136
MEN1 0 1.080 -1.150 0.101 0.684 -0.063
MEN1 0 1.080 -1.150 0.395
MEN1 0 1.080 -1.150
BHLHE40 0 -0.330 0.040
EGLN1 0 0.180 -0.270 -1.041
RB1 0 1.180 -1.070 0.429 0.755
RB1 0 1.180 -1.070
TCF7L2 0 -0.550 0.790 -0.741
CEBPG 0 -1.150 1.620
HAND2 0 0.000 0.600
TAF3 0 -0.260 -0.410 -0.724 -0.346
BTRC 0 -0.780 0.690 0.532 -1.791 0.313
TRIB1 0 -0.220 -0.430
CTNNBIP1 0 0.180 -0.150
GAS6 0 0.020 0.220 -1.517 -0.502
PBX1 0 -0.600 0.280
PBX1 0 -0.600 0.280 -0.186 -0.124
PTCH1 0 0.630 -0.690

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BHLHE40 Ubiquitylation K159 -0.521 _EVLQYLAK(gl)HENTR_
BHLHE40 Ubiquitylation K262 -1.135 _SEQPCFK(gl)SDHGR_
BHLHE40 Phosphorylation S383 -2.162 _LPS(ph)PLPAHPSVDSSVLLQALKPIPPLNLETKD_
BTRC Ubiquitylation K466 0.325 _IVSGAYDGKIK(gl)_
CEBPG Ubiquitylation K98 -0.339 _VNQLK(gl)EENERLEAK_
CEBPG Ubiquitylation K113 0.032 0.273 _LLTK(gl)ELSVLK_
CTNNBIP1 Ubiquitylation K19 -1.489 _EGAPGKSPEEMYIQQK(gl)VR_
EGLN1 Phosphorylation S12 -1.100 -0.639 _(ac)ANDSGGPGGPS(ph)PSER_
EGLN1 Phosphorylation S125 -1.027 -0.755 _AKPPADPAAAAS(ph)PCR_
HAND2 Ubiquitylation K183 0.800 1.236 _K(gl)ELNEILK_
HDAC2 Ubiquitylation K50 0.036 _K(gl)MEIYRPHK_
HDAC2 Ubiquitylation K67 -0.467 _ATAEEMTK(gl)YHSDEYIK_
HDAC2 Ubiquitylation K89 0.749 -0.241 _SIRPDNMSEYSK(gl)QMQR_
HDAC2 Ubiquitylation K284 0.749 _GHAK(gl)CVEVVK_
HDAC2 Phosphorylation S394 -0.865 -0.997 _M(ox)LPHAPGVQM(ox)QAIPEDAVHEDS(ph)GDEDGEDPDKR_
HDAC2 Phosphorylation S422 0.482 0.781 _IACDEEFS(ph)DSEDEGEGGR_
HDAC4 Phosphorylation S265 -0.390 _RS(ph)SPLLR_
HDAC4 Phosphorylation S266 -0.821 -0.598 _RSS(ph)PLLR_
HDAC4 Phosphorylation S632 -1.146 -0.837 _AQS(ph)SPASATFPVSVQEPPTKPR_
HMOX1 Ubiquitylation K243 -0.972 _ASNK(gl)VQDSAPVETPR_
HMOX1 Ubiquitylation K256 -1.769 _GK(gl)PPLNTR_
ID2 Phosphorylation S14 -0.139 _NS(ph)LSDHSLGISR_
KAT6A Phosphorylation S473 2.569 _LFGS(ph)QEIMTEK_
KAT6A Phosphorylation S1001 -0.884 -0.411 _SSS(ph)PPILTKPTLK_
KAT6A Phosphorylation S1089 0.499 0.643 _RLS(ph)SQDVLR_
KAT6A Phosphorylation S1090 0.740 1.024 _RLSS(ph)QDVLR_
KAT6A Phosphorylation S1113 -0.700 _SKDEEEDEES(ph)DDADDTPILKPVSLLR_
KDM1A Phosphorylation S69 -2.048 -2.645 _KEPPRAS(ph)PPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGR_
KDM1A Phosphorylation T88 -1.832 _KEPPRASPPGGLAEPPGSAGPQAGPT(ph)VVPGSATPM(ox)ETGIAETPEGR_
KDM1A Phosphorylation S126 0.780 0.501 _EMDES(ph)LANLSEDEYYS(ph)EEER_
KDM1A Phosphorylation S131 0.204 0.473 _EM(ox)DESLANLS(ph)EDEYYS(ph)EEER_
KDM1A Phosphorylation S137 0.122 0.511 _EM(ox)DESLANLS(ph)EDEYYS(ph)EEER_
KDM1A Phosphorylation S166 -2.328 -2.624 _KLPPPPPQAPPEEENES(ph)EPEEPSGVEGAAFQSR_
KDM1A Ubiquitylation K296 -0.820 _IKPLPTK(gl)K_
KDM1A Ubiquitylation K297 -0.820 _IKPLPTK(gl)K_
KDM1A Ubiquitylation K507 -1.073 _DITAEFLVKSK(gl)_
MAD2L2 Ubiquitylation K44 1.121 _EVYPVGIFQK(gl)R_
MEN1 Ubiquitylation K8 -1.132 0.088 _AAQK(gl)TLFPLR_
MEN1 Phosphorylation S218 -0.820 _RES(ph)KPEEPPPPK_
PBX1 Ubiquitylation K164 -0.541 _SK(gl)LAQIR_
PBX1 Ubiquitylation K195 -1.614 _TRPISPK(gl)EIER_
PBX2 Ubiquitylation K164 -0.541 _SK(gl)LAQIR_
PEX14 Phosphorylation S232 1.626 _RQFPPS(ph)PSAPK_
PEX14 Phosphorylation S234 3.951 _RQFPPSPS(ph)APK_
PROX1 Phosphorylation S511 0.460 0.502 _DRAS(ph)PESLDLTR_
PTCH1 Ubiquitylation K904 -0.390 _DKPIDISQLTK(gl)QR_
RB1 Phosphorylation S69 -3.602 -3.397 _TAATAAAAAAEPPAPPPPPPPEEDPEQDS(ph)GPEDLPLVR_
RB1 Ubiquitylation K97 -0.546 _LK(gl)IPDHVR_
RB1 Phosphorylation T388 0.005 0.116 _TLQTDSIDSFETQRT(ph)PR_
RB1 Phosphorylation T405 -0.851 -0.901 _KSNLDEEVNVIPPHT(ph)PVR_
RB1 Phosphorylation S820 -0.019 _S(ph)PYKFPSSPLR_
RB1 Ubiquitylation K823 -2.214 _SPYK(gl)FPSSPLR_
RB1 Phosphorylation S827 0.824 0.111 _FPSS(ph)PLR_
RB1 Phosphorylation S839 -0.701 -1.045 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K842 -0.751 _IPGGNIYISPLK(gl)SPYK_
RB1 Phosphorylation S843 -0.701 -0.022 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K846 -2.084 _SPYK(gl)ISEGLPTPTK_
RB1 Phosphorylation T853 0.039 -0.555 _ISEGLPT(ph)PTKM(ox)T(ph)PR_
RB1 Ubiquitylation K856 -1.350 _ISEGLPTPTK(gl)MTPR_
RB1 Phosphorylation T858 -0.782 0.564 _ISEGLPT(ph)PTKMT(ph)PR_
RB1 Ubiquitylation K879 -0.187 _FQK(gl)INQMVCNSDR_
RLIM Phosphorylation S228 -0.682 -0.653 _S(ph)RSPLHPM(ox)SEIPR_
RLIM Phosphorylation S230 -0.901 -0.673 _SRS(ph)PLHPM(ox)SEIPR_
RLIM Ubiquitylation K550 -0.777 -0.113 _GLTK(gl)EQIDNLAMR_
RLIM Ubiquitylation K582 -0.004 -0.263 _TCSVCITEYTEGNK(gl)LR_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_
SUFU Ubiquitylation K303 -0.015 _RLSGK(gl)DTEQIR_
SUFU Ubiquitylation K321 -1.917 -1.398 _GLEINSK(gl)PVLPPINPQR_
SUFU Phosphorylation S346 0.344 0.498 _KDS(ph)LESDSSTAIIPHELIR_
SUMO1 Phosphorylation S2 0.441 0.416 _(ac)S(ph)DQEAKPSTEDLGDKK_
SUMO1 Ubiquitylation K7 -0.850 -1.885 _(ac)SDQEAK(gl)PSTEDLGDKK_
SUMO1 Ubiquitylation K16 -0.686 -1.532 _(ac)SDQEAKPSTEDLGDK(gl)KEGEYIK_
SUMO1 Ubiquitylation K17 -0.857 -1.847 _(ac)SDQEAKPSTEDLGDKK(gl)EGEYIK_
SUMO1 Ubiquitylation K23 0.713 -0.346 _EGEYIK(gl)LK_
SUMO1 Ubiquitylation K37 0.417 _VIGQDSSEIHFK(gl)VK_
SUMO1 Ubiquitylation K45 0.975 _MTTHLK(gl)K_
SUMO1 Ubiquitylation K46 0.647 _K(gl)LKESYCQR_
SUMO1 Ubiquitylation K48 -0.241 -0.185 _LK(gl)ESYCQR_
TAF3 Phosphorylation S183 -0.112 _RPLDS(ph)PEAEELPAMK_
TAF3 Phosphorylation S229 -1.137 _IPPMLS(ph)PVHVQDSTDLAPPS(ph)PEPPM(ox)LAPVAK_
TAF3 Phosphorylation S243 -1.351 _IPPMLS(ph)PVHVQDSTDLAPPS(ph)PEPPM(ox)LAPVAK_
TAF3 Phosphorylation S297 -0.096 0.222 _TAQSPAMVGS(ph)PIR_
TCF7L2 Ubiquitylation K88 -0.867 -0.222 _ESLEEAAK(gl)R_
TRIB1 Ubiquitylation K46 -2.031 -0.877 _LLDADDAAAVAAK(gl)CPR_
TWIST1 Ubiquitylation K150 -0.176 _IQTLK(gl)LAAR_
WFS1 Phosphorylation S32 1.184 1.098 _LNATAS(ph)LEQER_
WFS1 Ubiquitylation K143 0.703 _EAVK(gl)LLR_


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