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Query: TRIB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRIB1 0 -2.908 -0.220 -0.430

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRIB1 Ubiquitylation K46 -2.031 -0.877 _LLDADDAAAVAAK(gl)CPR_

Background Information for TRIB1:


Pubmed-TRIB1 »
Uniprot-TRIB1 »
Biogrid-TRIB1 »
ProteomicsDB-TRIB1 »

Tumorportal-TRIB1 »
COSMIC-TRIB1 »
GenomeRNAi-TRIB1 »
Genecards-TRIB1


Protein-protein Interactions for TRIB1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BECN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1L2 Cat. description Hein, Mann, Cell 2015
Category members IP bait LLGL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MORC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLAIN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait STK17B Cat. description Hein, Mann, Cell 2015
Category members IP bait FOSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JUNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRIB1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0


Protein complexes (CORUM database) featuring TRIB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TRIB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity Database 0.18
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004860 protein kinase inhibitor activity Database 0.03
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0007254 JNK cascade Database 0
Category members GO Category GO:0014912 negative regulation of smooth muscle cell migration Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0031434 mitogen-activated protein kinase kinase binding Database 0
Category members GO Category GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway Database 0
Category members GO Category GO:0043405 regulation of MAP kinase activity Database 0
Category members GO Category GO:0048662 negative regulation of smooth muscle cell proliferation Database 0
Category members GO Category GO:0055106 ubiquitin-protein ligase regulator activity Database 0


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