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Results for the Category
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PSMD10 2 -1.900 3.850 0.390 2.518
VCP 2 1.650 -0.640 -0.182 0.578 -0.596 0.007 -0.036
PLK1 2 3.098 -0.387 0.212 -1.949 -0.610
HSPBP1 1 0.630 -0.340 -0.096 -0.788 0.132 2.885 1.233
GNB2L1 1 1.000 -0.100 0.279 1.704
GNB2L1 1 1.000 -0.100 -0.278 -0.107 -0.424
NUB1 0 -0.690 0.650
PIAS1 0 -1.020 1.720 -1.034 -0.678 0.471 -0.051 1.019
PSEN1 0 0.930 -1.110
STUB1 0 -1.420 2.320 -0.284 0.442 -0.104
SUMO1 0 0.450 0.060 -0.088 0.599 0.276 0.608 0.499
MDM2 0 -0.210 0.080
BBS7 0
CSNK1D 0 0.340 -0.060 0.150 0.527
CSNK1D 0 0.340 -0.060
CSNK1D 0 0.340 -0.060 1.237 -0.682 -0.148
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
PLK2 0 0.900 -0.790
TAF1 0 0.381 0.385
DAB2 0 0.510 -0.470
RCHY1 0 -0.710 1.020
RNF180 0 -0.170 0.320
UBE2V2 0 -0.070 0.120
TRIB1 0 -0.220 -0.430
LRRK2 0 0.530 -0.620 -0.240
CSNK1E 0 -0.170 -0.440 0.150 0.527
CSNK1E 0 -0.170 -0.440 1.237 -0.682 -0.148

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
BBS7 Ubiquitylation K59 -1.507 _KGEAAAVFK(gl)TLPGPK_
BBS7 Ubiquitylation K479 -0.952 _IQPK(gl)TCQVR_
BBS7 Ubiquitylation K685 -0.505 _FK(gl)GTNVK_
CSNK1D Ubiquitylation K43 -1.168 _LECVK(gl)TK_
CSNK1D Ubiquitylation K45 -1.168 _LECVK(gl)TK_
CSNK1D Ubiquitylation K140 -0.969 _DVKPDNFLMGLGK(gl)K_
CSNK1D Ubiquitylation K141 -0.969 -0.720 _DVKPDNFLMGLGKK(gl)_
CSNK1D Phosphorylation S350 -0.790 _LRGTQEVAPPTPLTPTS(ph)HTANTSPRPVSGM(ox)ER_
CSNK1D Phosphorylation S363 -0.662 -0.352 _IQPAGNTS(ph)PR_
CSNK1D Phosphorylation S382 -0.647 -0.568 _GAPVNIS(ph)SSDLTGR_
CSNK1D Phosphorylation S389 0.394 0.817 _GAPANVS(ph)SSDLTGR_
CSNK1E Ubiquitylation K43 -1.168 _LECVK(gl)TK_
CSNK1E Ubiquitylation K45 -1.168 _LECVK(gl)TK_
CSNK1E Ubiquitylation K140 -0.969 _DVKPDNFLMGLGK(gl)K_
CSNK1E Ubiquitylation K141 -0.969 -0.720 _DVKPDNFLMGLGKK(gl)_
CSNK1E Phosphorylation S363 -0.662 -0.352 _IQPAGNTS(ph)PR_
CSNK1E Phosphorylation S389 0.394 0.817 _GAPANVS(ph)SSDLTGR_
DAB2 Phosphorylation S401 -0.704 -0.722 _SSPNPFVGS(ph)PPK_
GNB2L1 Ubiquitylation K38 -0.238 0.350 _DK(gl)TIIMWK_
GNB2L1 Ubiquitylation K106 -0.290 _RFVGHTK(gl)DVLSVAFSSDNR_
GNB2L1 Ubiquitylation K130 0.632 _TIK(gl)LWNTLGVCK_
GNB2L1 Ubiquitylation K175 -0.554 -0.015 _LVK(gl)VWNLANCK_
GNB2L1 Ubiquitylation K183 -0.161 -0.282 _VWNLANCK(gl)_
GNB2L1 Ubiquitylation K185 -0.061 -0.249 _VWNLANCKLK(gl)_
GNB2L1 Ubiquitylation K257 -0.288 _YWLCAATGPSIK(gl)_
GNB2L1 Ubiquitylation K271 0.756 -0.007 _IIVDELK(gl)QEVISTSSK_
HSPBP1 Ubiquitylation K140 -0.036 _EEVEQMK(gl)SCLR_
HSPBP1 Ubiquitylation K291 -0.487 _AMQQQVQK(gl)LK_
HSPBP1 Phosphorylation S397 0.212 1.127 _LLQTCFSS(ph)PADDSMDR_
MDM2 Phosphorylation S166 0.576 1.068 _AIS(ph)ETEENSDELSGER_
MDM2 Ubiquitylation K334 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K336 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K363 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K364 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K473 0.806 _NK(gl)PCPVCR_
NUB1 Ubiquitylation K222 0.087 0.536 _GLEILAK(gl)R_
NUB1 Ubiquitylation K266 0.861 _ALMLAMGYHEK(gl)GR_
NUB1 Ubiquitylation K336 0.337 -0.679 _KLNLAQK(gl)CFK_
NUB1 Ubiquitylation K353 0.201 0.148 _LVHIK(gl)GNCGK_
PIAS1 Ubiquitylation K60 -1.191 _AGCSPAVQMKIK(gl)_
PIAS1 Ubiquitylation K341 -1.248 _VSLLCPLGK(gl)MR_
PIAS1 Phosphorylation S490 -0.898 -0.944 _RTCPSLSPTS(ph)PLNNK_
PIAS1 Phosphorylation S505 0.198 -0.250 _GILSLPHQAS(ph)PVSR_
PLK1 Ubiquitylation K358 -2.258 _EK(gl)EEPVVR_
PLK1 Ubiquitylation K574 1.656 _LSLLEEYGCCK(gl)ELASR_
PLK2 Ubiquitylation K438 -0.272 _SGTPAVENK(gl)QQIGDAIR_
PSEN1 Phosphorylation S313 0.844 _VSKNS(ph)KYNAESTER_
PSEN1 Ubiquitylation K314 0.016 0.414 _NSK(gl)YNAESTER_
PSEN1 Phosphorylation S366 -0.340 0.055 _AAVQELSS(ph)SILAGEDPEER_
PSEN1 Phosphorylation S367 0.005 0.066 _AAVQELSSS(ph)ILAGEDPEER_
PSMD10 Ubiquitylation K30 0.195 0.473 _LEELKESILADK(gl)SLATR_
PSMD10 Ubiquitylation K221 0.332 _GGLGLILK(gl)R_
RCHY1 Ubiquitylation K135 0.341 _HK(gl)CIENVSR_
RNF180 Phosphorylation S228 0.590 0.106 _S(ph)HSLDLNISEK_
STUB1 Phosphorylation S19 0.041 0.082 _LGAGGGS(ph)PEKS(ph)PSAQELK_
STUB1 Ubiquitylation K22 0.017 -0.536 _LGAGGGSPEK(gl)SPSAQELK_
STUB1 Phosphorylation S23 0.078 0.165 _LGAGGGS(ph)PEKS(ph)PSAQELK_
STUB1 Ubiquitylation K30 -0.704 -0.765 _SPSAQELK(gl)EQGNR_
STUB1 Ubiquitylation K41 -0.158 _K(gl)YPEAAACYGR_
STUB1 Ubiquitylation K125 0.325 -0.191 _AYSLAK(gl)EQR_
STUB1 Phosphorylation S273 -0.431 -0.250 _S(ph)PLTQEQLIPNLAMK_
SUMO1 Phosphorylation S2 0.441 0.416 _(ac)S(ph)DQEAKPSTEDLGDKK_
SUMO1 Ubiquitylation K7 -0.850 -1.885 _(ac)SDQEAK(gl)PSTEDLGDKK_
SUMO1 Ubiquitylation K16 -0.686 -1.532 _(ac)SDQEAKPSTEDLGDK(gl)KEGEYIK_
SUMO1 Ubiquitylation K17 -0.857 -1.847 _(ac)SDQEAKPSTEDLGDKK(gl)EGEYIK_
SUMO1 Ubiquitylation K23 0.713 -0.346 _EGEYIK(gl)LK_
SUMO1 Ubiquitylation K37 0.417 _VIGQDSSEIHFK(gl)VK_
SUMO1 Ubiquitylation K45 0.975 _MTTHLK(gl)K_
SUMO1 Ubiquitylation K46 0.647 _K(gl)LKESYCQR_
SUMO1 Ubiquitylation K48 -0.241 -0.185 _LK(gl)ESYCQR_
TAF1 Phosphorylation S547 -1.176 _LLEPPVLTLDPNDENLILEIPDEKEEATSNSPS(ph)K_
TAF1 Phosphorylation S550 -1.343 _LLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKES(ph)K_
TAF1 Phosphorylation S1176 0.662 1.114 _DDDTASVTS(ph)LNSSATGR_
TAF1 Phosphorylation T1703 0.001 -0.298 _DASVFQDESNM(ox)SVLDIPSAT(ph)PEK_
TRIB1 Ubiquitylation K46 -2.031 -0.877 _LLDADDAAAVAAK(gl)CPR_
UBE2V2 Ubiquitylation K8 -0.337 -0.243 _(ac)AVSTGVK(gl)VPR_
UBE2V2 Ubiquitylation K66 -0.608 _IYSLK(gl)VECGPK_
UBE2V2 Ubiquitylation K72 -0.575 -0.545 _VECGPK(gl)YPEAPPSVR_
UBE2V2 Ubiquitylation K129 0.440 0.709 _LMMSK(gl)ENMK_
VCP Phosphorylation S3 0.795 1.142 _(ac)AS(ph)GADSKGDDLSTAILK_
VCP Phosphorylation S7 0.312 0.941 _(ac)ASGADS(ph)KGDDLSTAILK_
VCP Ubiquitylation K8 -0.439 -0.154 _(ac)ASGADSK(gl)GDDLSTAILK_
VCP Ubiquitylation K18 -0.452 0.181 _GDDLSTAILK(gl)QK_
VCP Ubiquitylation K20 -0.512 0.529 _(ac)ASGADSKGDDLSTAILKQK(gl)_
VCP Ubiquitylation K60 0.678 0.493 _GDTVLLK(gl)GKK_
VCP Ubiquitylation K81 0.084 _EAVCIVLSDDTCSDEK(gl)IR_
VCP Ubiquitylation K109 -0.847 -0.260 _LGDVISIQPCPDVK(gl)YGK(gl)R_
VCP Ubiquitylation K112 -0.736 -0.276 _LGDVISIQPCPDVK(gl)YGK(gl)R_
VCP Ubiquitylation K148 -0.262 -0.087 _K(gl)GDIFLVR_
VCP Ubiquitylation K211 1.383 0.902 _K(gl)QLAQIK_
VCP Ubiquitylation K236 -0.526 -0.178 _AIGVK(gl)PPR_
VCP Ubiquitylation K251 -0.110 _GILLYGPPGTGK(gl)TLIAR_
VCP Ubiquitylation K336 0.522 _IVSQLLTLMDGLK(gl)QR_
VCP Ubiquitylation K386 1.339 0.706 _LEILQIHTK(gl)NM(ox)K_
VCP Ubiquitylation K389 0.568 1.195 _LEILQIHTKNMK(gl)_
VCP Ubiquitylation K505 0.377 0.794 _FLK(gl)FGMTPSK_
VCP Ubiquitylation K524 -0.528 _GVLFYGPPGCGK(gl)TLLAK_
VCP Ubiquitylation K529 -0.250 _GVLFYGPPGCGKTLLAK(gl)_
VCP Ubiquitylation K565 0.645 0.689 _EIFDK(gl)AR_
VCP Ubiquitylation K615 1.209 1.270 _VINQILTEMDGMSTKK(gl)_
VCP Ubiquitylation K651 -1.709 -0.719 _LDQLIYIPLPDEK(gl)SR_
VCP Ubiquitylation K658 0.362 0.711 _VAILK(gl)ANLR_
VCP Ubiquitylation K663 -0.839 _K(gl)SPVAKDVDLEFLAK_
VCP Ubiquitylation K668 -0.536 0.265 _SPVAK(gl)DVDLEFLAK_
VCP Ubiquitylation K696 1.574 1.691 _ACK(gl)LAIR_
VCP Ubiquitylation K754 0.510 0.939 _K(gl)YEMFAQTLQQSR_


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