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Query: PLK2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLK2 0 -0.272 0.900 -0.790

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLK2 Ubiquitylation K438 -0.272 _SGTPAVENK(gl)QQIGDAIR_

Background Information for PLK2:


Pubmed-PLK2 »
Uniprot-PLK2 »
Biogrid-PLK2 »
ProteomicsDB-PLK2 »

Tumorportal-PLK2 »
COSMIC-PLK2 »
GenomeRNAi-PLK2 »
Genecards-PLK2


Protein-protein Interactions for PLK2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PLK2 Cat. description Hein, Mann, Cell 2015


Protein Domains in PLK2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members POLO_box_duplicated_dom IPR000959 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring PLK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PLK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0007052 mitotic spindle organization Database 0.41
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0007093 mitotic cell cycle checkpoint Database 0.27
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0048167 regulation of synaptic plasticity Database 0.14
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0005814 centriole Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0007613 memory Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0032486 Rap protein signal transduction Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0046599 regulation of centriole replication Database 0
Category members GO Category GO:0060291 long-term synaptic potentiation Database 0
Category members GO Category GO:0060292 long term synaptic depression Database 0


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