RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
MAPK14	2	-0.160	-0.350
SHOC2	1	0.170	-0.260	1.791			-1.060	0.207
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
MAP2K1	1	-1.590	2.780
NRAS	1	1.810	-0.720				0.246	-0.346
RALA	0	-0.480	0.600				0.727	0.398
PLD1	0	-0.150	-0.140
GNB1	0	-0.700	0.650	0.713			0.504	0.538
GNB3	0	-1.020	1.280	0.713			0.504	0.538
MAPKAPK5	0	1.100	-0.730
BRAP	0	1.580	-1.050
CRKL	0	0.290	-0.620
MAPK3	0
SOS1	0	0.500	-0.620	-0.570
DHCR24	0	1.100	-0.830				0.024	-0.083
CDK2	0	-0.040	-0.300				-0.578	-0.797
CDK2	0	-0.040	-0.300	-0.202	-0.884	-0.107	-0.097	-0.501
CDKN1A	0	1.080	-0.750
RREB1	0	0.330	-0.460	-0.201			-0.613	-0.165
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
SDCBP	0	-1.190	2.010				-1.188	0.299
SDCBP	0	-1.190	2.010					-0.575
PLCE1	0	0.540	-0.070
USP8	0	0.830	-0.320
G3BP2	0	-0.700	1.500
G3BP2	0	-0.700	1.500	-0.506			-1.163	-0.750
RB1	0	1.180	-1.070		0.429	0.755
RB1	0	1.180	-1.070
KSR1	0	0.100	0.600
TP53	0	-1.070	1.050	-2.808	0.076	-0.094	0.436	0.497
RALB	0	-0.960	2.060
CCNA2	0	-0.530	0.260
PLK2	0	0.900	-0.790
G3BP1	0	-1.510	1.890	0.496	1.155	0.123	-0.821	-0.258
G3BP1	0	-1.510	1.890
CDKN2A	0	-0.080	-0.260	-0.556		-1.080	-3.270	-1.110
RSU1	0	-0.550	0.420		0.638	-0.925
RASGRP3	0	0.570	0.240
RAPGEF6	0	0.070	-0.270
YWHAB	0				0.628	-0.543
YWHAB	0			0.507			0.271	0.503
CDK1	0	-0.370	0.080	-0.202	-0.884	-0.107	-0.097	-0.501
HRAS	0	1.470	-0.520
ULK1	0	0.740	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
IQGAP3	0	1.720	-1.070				0.165	0.274
NF1	0	1.000	-0.500				0.444	-0.190
SRC	0	0.050	0.470	-0.031

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
BRAP	Phosphorylation	S157	0.033	-0.074	_ECINAAPDS(ph)PSK_
BRAP	Phosphorylation	S159	-0.208	-0.105	_ECINAAPDSPS(ph)K_
BRAP	Ubiquitylation	K425	0.929		_TDGK(gl)IVQYECEGDTCQEEK_
BRAP	Ubiquitylation	K466	0.347		_IYWENK(gl)IVR_
CCNA2	Ubiquitylation	K54		-0.746	_AALAVLK(gl)SGNPR_
CCNA2	Ubiquitylation	K68		-1.274	_GLAQQQRPK(gl)TR_
CDK1	Ubiquitylation	K6	0.011	-0.784	_(ac)M(ox)EDYTK(gl)IEK_
CDK1	Ubiquitylation	K20	-0.327	-0.270	_IGEGTYGVVYK(gl)GR_
CDK1	Ubiquitylation	K33	0.736	0.239	_TTGQVVAMK(gl)K_
CDK1	Ubiquitylation	K34		-0.306	_TTGQVVAMKK(gl)_
CDK1	Ubiquitylation	K58	0.312	-0.262	_EISLLK(gl)ELR_
CDK1	Ubiquitylation	K136		-0.468	_DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K145	0.161	-0.954	_DLKPQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K149		-0.038	_GTIK(gl)LADFGLAR_
CDK1	Ubiquitylation	K251	-0.047	-1.236	_WK(gl)PGSLASHVK_
CDK1	Ubiquitylation	K280	0.179	-1.210	_MLIYDPAK(gl)R_
CDK2	Ubiquitylation	K6	-0.130	-0.399	_(ac)MENFQK(gl)VEK_
CDK2	Ubiquitylation	K6	0.011	-0.784	_(ac)M(ox)EDYTK(gl)IEK_
CDK2	Phosphorylation	T14	0.429		_IGEGT(ph)YGVVYK_
CDK2	Phosphorylation	Y15	0.697	0.743	_IGEGTY(ph)GVVYK_
CDK2	Ubiquitylation	K20		0.272	_IGEGTYGVVYK(gl)AR_
CDK2	Ubiquitylation	K20	-0.327	-0.270	_IGEGTYGVVYK(gl)GR_
CDK2	Ubiquitylation	K24	0.366		_NK(gl)LTGEVVALKK_
CDK2	Ubiquitylation	K33		0.033	_NKLTGEVVALK(gl)K_
CDK2	Ubiquitylation	K33	0.736	0.239	_TTGQVVAMK(gl)K_
CDK2	Ubiquitylation	K34		0.542	_LTGEVVALKK(gl)_
CDK2	Ubiquitylation	K34		-0.306	_TTGQVVAMKK(gl)_
CDK2	Ubiquitylation	K58	0.312	-0.262	_EISLLK(gl)ELR_
CDK2	Ubiquitylation	K136		-0.468	_DLK(gl)PQNLLIDDK(gl)GTIK_
CDK2	Ubiquitylation	K145	0.161	-0.954	_DLKPQNLLIDDK(gl)GTIK_
CDK2	Ubiquitylation	K149		-0.038	_GTIK(gl)LADFGLAR_
CDK2	Ubiquitylation	K251	-0.047	-1.236	_WK(gl)PGSLASHVK_
CDK2	Ubiquitylation	K280	0.179	-1.210	_MLIYDPAK(gl)R_
CDK2	Ubiquitylation	K298	-1.907	-2.380	_QDFSK(gl)VVPPLDEDGR_
CDKN1A	Ubiquitylation	K188	-2.505	-1.077	_QTSMTDFYHSK(gl)R_
CRKL	Phosphorylation	S41		0.868	_DS(ph)STCPGDYVLSVSENSR_
CRKL	Phosphorylation	S107	-0.818	-1.177	_YPS(ph)PPMGSVSAPNLPTAEDNLEYVR_
DHCR24	Ubiquitylation	K76	-0.970	0.315	_VRDIQK(gl)QVR_
DHCR24	Ubiquitylation	K254		-0.170	_GLEAICAK(gl)FTHESQR_
DHCR24	Ubiquitylation	K313		0.393	_HVENYLK(gl)TNR_
DHCR24	Ubiquitylation	K367	-0.346	-0.263	_ISLLK(gl)LTQGETLR_
DHCR24	Ubiquitylation	K459	-0.920	-0.275	_QLEK(gl)FVR_
DHCR24	Ubiquitylation	K496	-0.539	-0.460	_EK(gl)LGCQDAFPEVYDK_
DHCR24	Ubiquitylation	K509		-0.754	_LGCQDAFPEVYDK(gl)ICK_
G3BP1	Ubiquitylation	K5	-0.296		_VMEK(gl)PSPLLVGR_
G3BP1	Ubiquitylation	K50	-0.885	-0.279	_NSSYVHGGLDSNGK(gl)PADAVYGQK_
G3BP1	Ubiquitylation	K64	0.737		_K(gl)VM(ox)SQNFTNCHTK_
G3BP1	Ubiquitylation	K76	0.373	0.769	_VM(ox)SQNFTNCHTK(gl)IR_
G3BP1	Phosphorylation	T143	-0.277		_YQDEVFGGFVT(ph)EPQEESEEEVEEPEER_
G3BP1	Phosphorylation	S149	-0.519	-0.267	_YQDEVFGGFVTEPQEES(ph)EEEVEEPEER_
G3BP1	Phosphorylation	S230	-0.445		_S(ph)SSPAPADIAQTVQEDLR_
G3BP1	Phosphorylation	S231	-0.108	-0.356	_SS(ph)SPAPADIAQTVQEDLR_
G3BP1	Phosphorylation	S232	-0.357	-0.128	_SSS(ph)PAPADIAQTVQEDLR_
G3BP1	Phosphorylation	T241	-0.320	-0.238	_SSSPAPADIAQT(ph)VQEDLR_
G3BP2	Phosphorylation	T227	-1.815	-1.898	_STT(ph)PPPAEPVSLPQEPPKPR_
GNB1	Ubiquitylation	K23	-0.282		_K(gl)ACADATLSQITNNIDPVGR_
GNB1	Ubiquitylation	K209	-0.296	-0.249	_LFVSGACDASAK(gl)LWDVR_
GNB3	Ubiquitylation	K23	-0.282		_K(gl)ACADATLSQITNNIDPVGR_
GNB3	Ubiquitylation	K209	-0.296	-0.249	_LFVSGACDASAK(gl)LWDVR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
IQGAP3	Ubiquitylation	K661		0.344	_ALESAMAKK(gl)_
IQGAP3	Phosphorylation	T1426		-0.517	_SLT(ph)AHSLLPLAEK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
KSR1	Phosphorylation	S334		0.052	_FDLSHGS(ph)PQMVR_
KSR1	Phosphorylation	S406	-0.052	-0.067	_RTES(ph)VPSDINNPVDR_
KSR1	Phosphorylation	S569	-0.413	-0.383	_ADVLEAHEAEAEEPEAGKS(ph)EAEDDEDEVDDLPSSR_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK14	Phosphorylation	S2	3.221	3.623	_(ac)S(ph)QERPTFYR_
MAPK14	Phosphorylation	T180	0.958	1.087	_HTDDEM(ox)T(ph)GYVATR_
MAPK14	Phosphorylation	Y182	1.388	1.374	_HTDDEM(ox)TGY(ph)VATR_
MAPK14	Ubiquitylation	K249	0.073	-1.380	_LVGTPGAELLKK(gl)_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
MAPKAPK5	Phosphorylation	T182	-0.559	-0.706	_IDQGDLM(ox)T(ph)PQFTPYYVAPQVLEAQR_
NF1	Ubiquitylation	K471		0.218	_MAPSLTFKEK(gl)_
NF1	Phosphorylation	S864		-0.458	_SNSGLATYS(ph)PPMGPVSER_
NF1	Phosphorylation	T2514		0.076	_GSEGYLAATYPTVGQT(ph)SPR_
NF1	Phosphorylation	S2515	0.071	0.316	_GSEGYLAATYPTVGQTS(ph)PR_
NF1	Phosphorylation	S2543	0.698	0.655	_S(ph)FDHLISDTK_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PLCE1	Phosphorylation	S1096	-0.120	0.294	_GES(ph)GEVTDDEMATR_
PLD1	Ubiquitylation	K501		-0.155	_LTDVGSVK(gl)R_
PLD1	Ubiquitylation	K547	0.453	1.120	_SIDDVDSK(gl)LK_
PLD1	Ubiquitylation	K549		1.120	_SIDDVDSK(gl)LK_
PLD1	Ubiquitylation	K1000	-0.600		_NATIYDK(gl)VFR_
PLK2	Ubiquitylation	K438		-0.272	_SGTPAVENK(gl)QQIGDAIR_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RALA	Ubiquitylation	K7	0.700		_(ac)AANKPK(gl)GQNSLALHK_
RALA	Ubiquitylation	K134	0.656	-0.585	_SDLEDK(gl)RQVSVEEAK_
RALA	Ubiquitylation	K143		-0.388	_QVSVEEAK(gl)NR_
RALB	Ubiquitylation	K29	0.645		_SK(gl)GQSSLALHK_
RAPGEF6	Phosphorylation	S280	-0.583	-0.664	_LPEGPVDS(ph)EDDEEEDEEIDRTDPLQGR_
RAPGEF6	Phosphorylation	S1120		0.074	_SLS(ph)QGSTNSNM(ox)LDVQGGAHKK_
RAPGEF6	Phosphorylation	S1144	1.135	0.460	_RSS(ph)LLNAK_
RAPGEF6	Phosphorylation	S1207	-1.222	-0.492	_SSEMS(ph)PVPMR_
RAPGEF6	Phosphorylation	S1544	-0.050	-0.196	_GLIVYCVTS(ph)PK_
RASGRP3	Phosphorylation	S390	0.183	0.695	_SPTS(ph)PTTPNK_
RB1	Phosphorylation	S69	-3.602	-3.397	_TAATAAAAAAEPPAPPPPPPPEEDPEQDS(ph)GPEDLPLVR_
RB1	Ubiquitylation	K97	-0.546		_LK(gl)IPDHVR_
RB1	Phosphorylation	T388	0.005	0.116	_TLQTDSIDSFETQRT(ph)PR_
RB1	Phosphorylation	T405	-0.851	-0.901	_KSNLDEEVNVIPPHT(ph)PVR_
RB1	Phosphorylation	S820		-0.019	_S(ph)PYKFPSSPLR_
RB1	Ubiquitylation	K823	-2.214		_SPYK(gl)FPSSPLR_
RB1	Phosphorylation	S827	0.824	0.111	_FPSS(ph)PLR_
RB1	Phosphorylation	S839	-0.701	-1.045	_IPGGNIYIS(ph)PLKS(ph)PYK_
RB1	Ubiquitylation	K842		-0.751	_IPGGNIYISPLK(gl)SPYK_
RB1	Phosphorylation	S843	-0.701	-0.022	_IPGGNIYIS(ph)PLKS(ph)PYK_
RB1	Ubiquitylation	K846	-2.084		_SPYK(gl)ISEGLPTPTK_
RB1	Phosphorylation	T853	0.039	-0.555	_ISEGLPT(ph)PTKM(ox)T(ph)PR_
RB1	Ubiquitylation	K856	-1.350		_ISEGLPTPTK(gl)MTPR_
RB1	Phosphorylation	T858	-0.782	0.564	_ISEGLPT(ph)PTKMT(ph)PR_
RB1	Ubiquitylation	K879	-0.187		_FQK(gl)INQMVCNSDR_
RREB1	Phosphorylation	S161	-0.718	-0.899	_IHEKDPNSATATAPPS(ph)PLK_
RREB1	Ubiquitylation	K763	-1.253		_LCGEDLK(gl)HYR_
RREB1	Phosphorylation	T1116	-0.250		_AATTAT(ph)PAATTSPK_
RREB1	Phosphorylation	S1167	0.831	0.515	_ANS(ph)GGVDLDSSGEFASIEK_
RREB1	Phosphorylation	S1219		-1.622	_FSPFLQTAEDNTQDEVAGAPADHHGPS(ph)DEEQGSPPEDK_
RREB1	Phosphorylation	S1320	-0.037	0.000	_QVAGDAPVEQATAETAS(ph)PVHR_
RREB1	Phosphorylation	S1653	-1.287	-1.742	_VTAGWPSEPGQGDLNPES(ph)PAALGQDLLEPR_
SDCBP	Phosphorylation	S6	0.120	0.427	_(ac)SLYPS(ph)LEDLKVDK_
SDCBP	Ubiquitylation	K35		-0.806	_(ac)SLYPSLEDLKVDK(gl)_
SDCBP	Ubiquitylation	K129	0.064	0.792	_RAEIK(gl)QGIR_
SDCBP	Ubiquitylation	K199	-0.134	-0.436	_VLK(gl)QAFGEK_
SDCBP	Ubiquitylation	K243	0.141		_ITSIVK(gl)DSSAAR_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
TP53	Ubiquitylation	K120	-0.188		_LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53	Ubiquitylation	K164	0.157	-1.260	_AMAIYK(gl)QSQHMTEVVR_
TP53	Phosphorylation	S314	-0.695	-1.000	_ALPNNTSS(ph)SPQPK_
TP53	Phosphorylation	S315	-0.762	-0.959	_RALPNNTSSS(ph)PQPK_
TP53	Ubiquitylation	K320	-0.978		_ALPNNTSSSPQPKK(gl)_
TP53	Ubiquitylation	K357	-0.231	-0.823	_ELNEALELKDAQAGK(gl)EPGGSR_
ULK1	Phosphorylation	S450	-0.237	-0.173	_NLQS(ph)PTQFQTPR_
ULK1	Phosphorylation	T468	-0.247	0.456	_SGST(ph)SPLGFAR_
ULK1	Phosphorylation	S469	0.035	0.470	_SGSTS(ph)PLGFAR_
ULK1	Phosphorylation	S623	-0.793	-0.874	_NPLPPILGS(ph)PTK_
ULK1	Phosphorylation	T625	-0.547	-0.776	_NPLPPILGSPT(ph)K_
ULK1	Phosphorylation	T636		0.087	_T(ph)PSSQNLLALLAR_
ULK1	Phosphorylation	S638	-0.154	0.598	_TPS(ph)SQNLLALLAR_
USP8	Phosphorylation	S392	-0.015	0.284	_SDVS(ph)PIIQPVPSIK_
USP8	Phosphorylation	T577	-0.048	0.069	_RCPT(ph)PEIQKK_
USP8	Phosphorylation	S716	0.750	0.023	_S(ph)YSSPDITQAIQEEEKR_
USP8	Phosphorylation	S718	0.338	0.273	_SYS(ph)SPDITQAIQEEEKR_
YWHAB	Ubiquitylation	K11	1.057	1.322	_(ac)TMDKSELVQK(gl)AK_
YWHAB	Ubiquitylation	K13	0.060	0.388	_AK(gl)LAEQAER_
YWHAB	Ubiquitylation	K70	0.558	-0.175	_VISSIEQK(gl)TER_
YWHAB	Ubiquitylation	K140		0.531	_YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB	Ubiquitylation	K159	0.300		_QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB	Ubiquitylation	K160	-0.439	-0.371	_K(gl)EMQPTHPIR_