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Query: RREB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RREB1 0 -0.886 0.330 -0.460 -0.201 -0.613 -0.165

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RREB1 Phosphorylation S1167 0.831 0.515 _ANS(ph)GGVDLDSSGEFASIEK_
RREB1 Phosphorylation S1320 -0.037 0.000 _QVAGDAPVEQATAETAS(ph)PVHR_
RREB1 Phosphorylation S161 -0.718 -0.899 _IHEKDPNSATATAPPS(ph)PLK_
RREB1 Phosphorylation S1219 -1.622 _FSPFLQTAEDNTQDEVAGAPADHHGPS(ph)DEEQGSPPEDK_
RREB1 Phosphorylation S1653 -1.287 -1.742 _VTAGWPSEPGQGDLNPES(ph)PAALGQDLLEPR_
RREB1 Ubiquitylation K763 -1.253 _LCGEDLK(gl)HYR_
RREB1 Phosphorylation T1116 -0.250 _AATTAT(ph)PAATTSPK_

Background Information for RREB1:





Protein-protein Interactions for RREB1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC23 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait SNW1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RREB1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92


Protein complexes (CORUM database) featuring RREB1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 642 CtBP complex Database 3.6
Category members Corum 626 LSD1 complex Database 0.17


Categories featuring RREB1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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