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Query: G3BP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
G3BP2 0 -4.632 -0.700 1.500
G3BP2 0 -4.632 -0.700 1.500 -0.506 -1.163 -0.750

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
G3BP2 Phosphorylation T227 -1.815 -1.898 _STT(ph)PPPAEPVSLPQEPPKPR_

Background Information for G3BP2:


Pubmed-G3BP2 »
Uniprot-G3BP2 »
Biogrid-G3BP2 »
ProteomicsDB-G3BP2 »

Tumorportal-G3BP2 »
COSMIC-G3BP2 »
GenomeRNAi-G3BP2 »
Genecards-G3BP2


Protein-protein Interactions for G3BP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait G3BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in G3BP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members NTF2 IPR002075 0
Category members Nuclear_transport_factor_2_euk IPR018222 0


Protein complexes (CORUM database) featuring G3BP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring G3BP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0007253 cytoplasmic sequestering of NF-kappaB Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0030159 receptor signaling complex scaffold activity Database 0


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