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Query: SDCBP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SDCBP 0 2.600 -1.190 2.010 -0.575
SDCBP 0 2.600 -1.190 2.010 -1.188 0.299

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SDCBP Ubiquitylation K129 0.064 0.792 _RAEIK(gl)QGIR_
SDCBP Phosphorylation S6 0.120 0.427 _(ac)SLYPS(ph)LEDLKVDK_
SDCBP Ubiquitylation K199 -0.134 -0.436 _VLK(gl)QAFGEK_
SDCBP Ubiquitylation K35 -0.806 _(ac)SLYPSLEDLKVDK(gl)_
SDCBP Ubiquitylation K243 0.141 _ITSIVK(gl)DSSAAR_

Background Information for SDCBP:


Pubmed-SDCBP »
Uniprot-SDCBP »
Biogrid-SDCBP »
ProteomicsDB-SDCBP »

Tumorportal-SDCBP »
COSMIC-SDCBP »
GenomeRNAi-SDCBP »
Genecards-SDCBP


Protein-protein Interactions for SDCBP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait C16orf58 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM8A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPRC5B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LITAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LTBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHB11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDCBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM223 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF10A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WRAP73 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SDCBP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PDZ IPR001478 0.15


Protein complexes (CORUM database) featuring SDCBP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SDCBP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0042470 melanosome Database 5.59
Category members GO Category GO:0047485 protein N-terminus binding Database 1.84
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0042327 positive regulation of phosphorylation Database 0.52
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0046875 ephrin receptor binding Database 0.3
Category members GO Category GO:0006612 protein targeting to membrane Database 0.29
Category members Pathway Pathway_1093 PID_SYNDECAN_4_PATHWAY 0 0.28
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0005912 adherens junction Database 0.25
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_1022 PID_SYNDECAN_2_PATHWAY 0 0.08
Category members Pathway Pathway_654 PID_IL5_PATHWAY 0 0.04
Category members Pathway Pathway_476 PID_SYNDECAN_1_PATHWAY 0 0
Category members GO Category GO:0001948 glycoprotein binding Database 0
Category members GO Category GO:0005109 frizzled binding Database 0
Category members GO Category GO:0005137 interleukin-5 receptor binding Database 0
Category members GO Category GO:0006930 substrate-dependent cell migration, cell extension Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0008093 cytoskeletal adaptor activity Database 0
Category members GO Category GO:0019838 growth factor binding Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0042043 neurexin family protein binding Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0045545 syndecan binding Database 0
Category members GO Category GO:0046330 positive regulation of JNK cascade Database 0
Category members GO Category GO:0050839 cell adhesion molecule binding Database 0


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