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Results for the Category
positive regulation of JNK cascade
(GO:0046330)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RIPK2 1 -1.740 3.580
FZD7 1 2.260 -1.160
TAOK1 1 -2.360 4.940 1.169
FLT4 0 0.940 -0.560
HIPK2 0 -0.990 0.680
CDC42 0 -0.170 0.490 -0.597 -1.527 -1.013
CDC42 0 1.240 -0.940 -0.597 -1.527 -1.013
TRAF4 0 -0.140 0.360
STK3 0 -0.570 0.720
STK3 0 -0.570 0.720 -0.235 -0.851
TPD52L1 0 -1.170 1.190
WNT5A 0
GADD45A 0 1.050 -0.170
TAOK3 0 -0.440 0.370
TAOK3 0 -0.440 0.370 1.169
MAP3K7 0 -1.120 1.140 -1.048
RIPK1 0 -0.190 0.440
SDCBP 0 -1.190 2.010 -1.188 0.299
SDCBP 0 -1.190 2.010 -0.575
MINK1 0 -0.710 0.650 0.038 0.092 0.062
MINK1 0 -0.710 0.650
TAOK2 0 -0.120 -0.070 1.017 -0.645
TAOK2 0 0.700 -0.640 1.017 -0.645
TAOK2 0 -0.120 -0.070
TAOK2 0 0.700 -0.640
F2RL1 0 -1.330 2.490
HRAS 0 1.470 -0.520
PLCB1 0 -0.300 -0.220

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CDC42 Ubiquitylation K173 -1.839 _DDPSTIEK(gl)LAK_
CDC42 Ubiquitylation K178 -0.801 -0.716 _NK(gl)QKPITPETAEK_
CDC42 Ubiquitylation K180 -1.806 _QK(gl)PITPETAEK(gl)LAR_
CDC42 Ubiquitylation K189 -1.082 _QKPITPETAEK(gl)LAR_
CDC42 Ubiquitylation K198 0.550 1.159 _AVK(gl)YVECSALTQK_
CDC42 Ubiquitylation K208 -0.937 0.038 _YVECSALTQK(gl)GLK_
CDC42 Ubiquitylation K228 -2.488 _NVFDEAILAALEPPEPK(gl)K_
CDC42 Ubiquitylation K229 -1.254 _NVFDEAILAALEPPEPKK(gl)_
F2RL1 Ubiquitylation K368 0.159 0.737 _TVK(gl)QMQVSLTSK_
F2RL1 Ubiquitylation K377 -0.040 -0.268 _QMQVSLTSK(gl)K_
F2RL1 Ubiquitylation K378 0.066 -0.268 _QMQVSLTSKK(gl)_
F2RL1 Phosphorylation S384 0.573 1.068 _KSS(ph)SYSSSSTTVK_
F2RL1 Ubiquitylation K394 0.350 0.873 _KSSSYSSSSTTVK(gl)TSY_
FLT4 Ubiquitylation K987 -0.270 _FSK(gl)TEGGAR_
FLT4 Ubiquitylation K1064 -1.119 _DIYK(gl)DPDYVR_
FZD7 Ubiquitylation K569 0.551 0.319 _LSHSSK(gl)GETAV_
GADD45A Ubiquitylation K12 -0.515 0.281 _TLEEFSAGEQK(gl)TER_
GADD45A Ubiquitylation K29 0.092 _VGDALEEVLSK(gl)ALSQR_
HIPK2 Ubiquitylation K492 -0.060 _YISQTQGLPAEYLLSAGTK(gl)TTR_
HIPK2 Ubiquitylation K614 -0.350 _SCFQNMEICK(gl)R_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
MINK1 Phosphorylation S763 0.045 -0.277 _SDSVLPASHGHLPQAGS(ph)LER_
PLCB1 Phosphorylation S1199 -0.494 _TPS(ph)SEELGGDIPGKEFDTPL_
PLCB1 Phosphorylation S1200 -0.483 _TPSS(ph)EELGGDIPGKEFDTPL_
RIPK1 Ubiquitylation K642 -0.431 _EGIK(gl)GATVGK_
RIPK2 Ubiquitylation K410 -2.810 _AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2 Phosphorylation S531 0.884 0.839 _SPS(ph)LNLLQNK_
RIPK2 Ubiquitylation K538 -2.659 _SPSLNLLQNK(gl)SM_
SDCBP Phosphorylation S6 0.120 0.427 _(ac)SLYPS(ph)LEDLKVDK_
SDCBP Ubiquitylation K35 -0.806 _(ac)SLYPSLEDLKVDK(gl)_
SDCBP Ubiquitylation K129 0.064 0.792 _RAEIK(gl)QGIR_
SDCBP Ubiquitylation K199 -0.134 -0.436 _VLK(gl)QAFGEK_
SDCBP Ubiquitylation K243 0.141 _ITSIVK(gl)DSSAAR_
STK3 Ubiquitylation K176 -0.350 _DIK(gl)AGNILLNTEGHAK_
STK3 Ubiquitylation K205 -0.223 -0.386 _LADFGVAGQLTDTMAK(gl)R_
STK3 Phosphorylation S344 0.416 0.115 _ELEEEEENS(ph)DEDELDSHTM(ox)VK_
STK3 Phosphorylation S344 0.573 0.366 _EMDQDDEENS(ph)EEDEMDSGTMVR_
STK3 Phosphorylation S413 0.603 1.205 _NATS(ph)PQVQRPSFMDYFDK_
STK3 Ubiquitylation K481 -0.782 _LK(gl)ALDPMMER_
TAOK1 Phosphorylation S9 -0.793 0.108 _AGS(ph)LKDPEIAELFFKEDPEK_
TAOK1 Phosphorylation S421 -0.535 -0.355 _ASDPQS(ph)PPQVSR_
TAOK1 Ubiquitylation K587 0.700 _QEWLSK(gl)QK_
TAOK2 Phosphorylation S9 0.024 0.070 _AGS(ph)LKDPDVAELFFKDDPEK_
TAOK3 Phosphorylation S9 -0.793 0.108 _AGS(ph)LKDPEIAELFFKEDPEK_
TAOK3 Phosphorylation S324 0.159 0.189 _NGPLNES(ph)QEDEEDSEHGTSLNR_
TAOK3 Phosphorylation S421 -0.535 -0.355 _ASDPQS(ph)PPQVSR_
TAOK3 Ubiquitylation K587 0.700 _QEWLSK(gl)QK_
TPD52L1 Phosphorylation T146 0.503 _NSPT(ph)FKSFEER_
TPD52L1 Phosphorylation S149 0.484 0.646 _NSPTFKS(ph)FEER_
TRAF4 Phosphorylation S426 0.249 _GS(ph)LDESSLGFGYPK_
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_


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