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Query: TAOK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TAOK1 1 6.382 -2.360 4.940 1.169

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TAOK1 Phosphorylation S9 -0.793 0.108 _AGS(ph)LKDPEIAELFFKEDPEK_
TAOK1 Phosphorylation S421 -0.535 -0.355 _ASDPQS(ph)PPQVSR_
TAOK1 Ubiquitylation K587 0.700 _QEWLSK(gl)QK_

Background Information for TAOK1:


Pubmed-TAOK1 »
Uniprot-TAOK1 »
Biogrid-TAOK1 »
ProteomicsDB-TAOK1 »

Tumorportal-TAOK1 »
COSMIC-TAOK1 »
GenomeRNAi-TAOK1 »
Genecards-TAOK1


Protein-protein Interactions for TAOK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C9orf6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TAOK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Homeodomain-like IPR009057 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring TAOK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TAOK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0004709 MAP kinase kinase kinase activity Database 0.08
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0051493 regulation of cytoskeleton organization Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1098 PID_P38_MKK3_6PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0031572 G2 DNA damage checkpoint Database 0
Category members GO Category GO:0032874 positive regulation of stress-activated MAPK cascade Database 0
Category members GO Category GO:0046330 positive regulation of JNK cascade Database 0


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