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Results for the Category
MAP kinase kinase kinase activity
(GO:0004709)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RAF1 1 2.020 -1.230
TAOK1 1 -2.360 4.940 1.169
ARAF 0 0.550 -0.670
ARAF 0 0.550 -0.670
MAP3K4 0 0.000 0.450
MAP3K1 0 0.750 -1.270
TAOK3 0 -0.440 0.370
TAOK3 0 -0.440 0.370 1.169
MAP3K7 0 -1.120 1.140 -1.048
MAP3K6 0 0.420 -0.050
EGFR 0 -0.580 0.520 0.513 0.090
TAOK2 0 -0.120 -0.070 1.017 -0.645
TAOK2 0 0.700 -0.640 1.017 -0.645
TAOK2 0 -0.120 -0.070
TAOK2 0 0.700 -0.640
BRAF 0
MAP3K2 0 -1.220 1.960
MAP3K5 0 0.710 -0.770
MAP3K3 0 0.830 -0.050

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ARAF Phosphorylation T227 0.017 _STSTPNVHMVSTT(ph)APMDSNLIQLTGQSFSTDAAGSR_
ARAF Phosphorylation S260 0.245 _GS(ph)PSPASVSSGR_
ARAF Ubiquitylation K543 -1.068 -0.962 _ISSNCPK(gl)AMR_
ARAF Phosphorylation S621 0.212 0.271 _SAS(ph)EPSLHR_
BRAF Phosphorylation S151 -0.685 -0.629 _SNPKS(ph)PQKPIVR_
BRAF Phosphorylation S363 -0.023 -0.241 _S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF Phosphorylation S365 -0.286 0.012 _SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF Phosphorylation S399 -0.890 -0.527 _GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF Phosphorylation T401 -0.525 _GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF Phosphorylation S446 0.246 0.349 _RDS(ph)SDDWEIPDGQITVGQR_
BRAF Phosphorylation S447 0.579 0.623 _RDSS(ph)DDWEIPDGQITVGQR_
BRAF Phosphorylation S729 0.208 0.219 _SAS(ph)EPSLNR_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MAP3K2 Phosphorylation S153 0.506 -0.231 _RLS(ph)IIGPTSR_
MAP3K2 Phosphorylation S163 -0.910 -0.776 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S164 -0.743 -0.966 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S239 -0.284 -0.618 _AQS(ph)YPDNHQEFSDYDNPIFEK_
MAP3K2 Phosphorylation S331 0.008 _RRGS(ph)DIDNPTLTVM(ox)DISPPSR_
MAP3K3 Phosphorylation S166 -0.325 _HLS(ph)VSSQNPGR_
MAP3K3 Phosphorylation S175 0.120 -0.091 _S(ph)SPPPGYVPER_
MAP3K3 Phosphorylation S176 0.120 -0.091 _S(ph)SPPPGYVPER_
MAP3K3 Phosphorylation S250 -0.070 _AQS(ph)FPDNR_
MAP3K4 Ubiquitylation K406 0.367 _DLNQK(gl)LR_
MAP3K4 Phosphorylation S1252 -0.654 _HSS(ph)PTEERDEPAYPR_
MAP3K5 Phosphorylation S1066 -1.241 _SISLPVPVLVEDTSSSSEYGSVS(ph)PDTELKVDPFSFK_
MAP3K5 Phosphorylation S1113 -1.408 -0.562 _TLFLGIPDENFEDHSAPPS(ph)PEEK_
MAP3K6 Phosphorylation S984 -0.616 -0.840 _VPEEPAAEEPAS(ph)PEESSGLSLLHQESK_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
RAF1 Phosphorylation S29 0.028 -0.571 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation T31 0.028 -0.669 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation S244 0.053 _YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1 Phosphorylation S259 -0.069 0.054 _STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1 Phosphorylation S301 -0.651 _SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1 Phosphorylation T303 -0.664 _SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1 Phosphorylation S497 -0.449 _SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1 Phosphorylation S621 0.212 0.271 _SAS(ph)EPSLHR_
RAF1 Phosphorylation S642 -0.197 0.463 _AAHTEDINACTLTTS(ph)PR_
TAOK1 Phosphorylation S9 -0.793 0.108 _AGS(ph)LKDPEIAELFFKEDPEK_
TAOK1 Phosphorylation S421 -0.535 -0.355 _ASDPQS(ph)PPQVSR_
TAOK1 Ubiquitylation K587 0.700 _QEWLSK(gl)QK_
TAOK2 Phosphorylation S9 0.024 0.070 _AGS(ph)LKDPDVAELFFKDDPEK_
TAOK3 Phosphorylation S9 -0.793 0.108 _AGS(ph)LKDPEIAELFFKEDPEK_
TAOK3 Phosphorylation S324 0.159 0.189 _NGPLNES(ph)QEDEEDSEHGTSLNR_
TAOK3 Phosphorylation S421 -0.535 -0.355 _ASDPQS(ph)PPQVSR_
TAOK3 Ubiquitylation K587 0.700 _QEWLSK(gl)QK_


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