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Query: MAP3K6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAP3K6 0 -1.456 0.420 -0.050

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAP3K6 Phosphorylation S984 -0.616 -0.840 _VPEEPAAEEPAS(ph)PEESSGLSLLHQESK_

Background Information for MAP3K6:


Pubmed-MAP3K6 »
Uniprot-MAP3K6 »
Biogrid-MAP3K6 »
ProteomicsDB-MAP3K6 »

Tumorportal-MAP3K6 »
COSMIC-MAP3K6 »
GenomeRNAi-MAP3K6 »
Genecards-MAP3K6


Protein-protein Interactions for MAP3K6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait XRCC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAP3K6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFSF13B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAP3K6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members SAM/pointed IPR013761 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MAP3K6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAP3K6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0000186 activation of MAPKK activity Database 0.16
Category members GO Category GO:0004709 MAP kinase kinase kinase activity Database 0.08
Category members GO Category GO:0007257 activation of JUN kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1000 BIOCARTA_MAPK_PATHWAY 0 0
Category members Pathway Pathway_1098 PID_P38_MKK3_6PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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