RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
PLCG1	1	-0.170	0.000
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
MAP2K1	1	-1.590	2.780
NRAS	1	1.810	-0.720				0.246	-0.346
EIF2AK2	0	-1.060	1.180	-0.657		-0.502	0.213	-0.027
PSEN1	0	0.930	-1.110
MAP3K4	0	0.000	0.450
MAP3K1	0	0.750	-1.270
CRKL	0	0.290	-0.620
MAPK3	0
TGFBR1	0	-0.260	0.020
RAPGEF1	0	1.620	-0.780
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
KIDINS220	0	0.490	-0.510				0.039	0.379
MAP3K7	0	-1.120	1.140	-1.048
MAP3K6	0	0.420	-0.050
EGFR	0	-0.580	0.520				0.513	0.090
TAOK2	0	-0.120	-0.070				1.017	-0.645
TAOK2	0	0.700	-0.640				1.017	-0.645
TAOK2	0	-0.120	-0.070
TAOK2	0	0.700	-0.640
BRAF	0
YWHAB	0				0.628	-0.543
YWHAB	0			0.507			0.271	0.503
CRK	0	-0.790	0.230
ADAM9	0	0.290	-0.290
MAP3K2	0	-1.220	1.960
CDK1	0	-0.370	0.080	-0.202	-0.884	-0.107	-0.097	-0.501
HRAS	0	1.470	-0.520
F2R	0	0.220	0.110
LRRK2	0	0.530	-0.620	-0.240
MAP3K5	0	0.710	-0.770
MAP3K3	0	0.830	-0.050

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ADAM9	Ubiquitylation	K741	0.269	0.229	_SQTYESDGK(gl)NQANPSRQPGSVPR_
ADAM9	Phosphorylation	S758	-0.375	-0.893	_HVS(ph)PVTPPR_
ADAM9	Phosphorylation	T761	-0.724	-0.397	_HVSPVT(ph)PPREVPIYANR_
ADAM9	Ubiquitylation	K781	-2.213		_FAVPTYAAK(gl)QPQQFPSRPPPPQPK_
BRAF	Phosphorylation	S151	-0.685	-0.629	_SNPKS(ph)PQKPIVR_
BRAF	Phosphorylation	S363	-0.023	-0.241	_S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S365	-0.286	0.012	_SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S399	-0.890	-0.527	_GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF	Phosphorylation	T401	-0.525		_GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF	Phosphorylation	S446	0.246	0.349	_RDS(ph)SDDWEIPDGQITVGQR_
BRAF	Phosphorylation	S447	0.579	0.623	_RDSS(ph)DDWEIPDGQITVGQR_
BRAF	Phosphorylation	S729	0.208	0.219	_SAS(ph)EPSLNR_
CDK1	Ubiquitylation	K6	0.011	-0.784	_(ac)M(ox)EDYTK(gl)IEK_
CDK1	Ubiquitylation	K20	-0.327	-0.270	_IGEGTYGVVYK(gl)GR_
CDK1	Ubiquitylation	K33	0.736	0.239	_TTGQVVAMK(gl)K_
CDK1	Ubiquitylation	K34		-0.306	_TTGQVVAMKK(gl)_
CDK1	Ubiquitylation	K58	0.312	-0.262	_EISLLK(gl)ELR_
CDK1	Ubiquitylation	K136		-0.468	_DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K145	0.161	-0.954	_DLKPQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K149		-0.038	_GTIK(gl)LADFGLAR_
CDK1	Ubiquitylation	K251	-0.047	-1.236	_WK(gl)PGSLASHVK_
CDK1	Ubiquitylation	K280	0.179	-1.210	_MLIYDPAK(gl)R_
CRK	Phosphorylation	S40	0.533	0.363	_DS(ph)STSPGDYVLSVSENSR_
CRK	Phosphorylation	S41	1.065	0.801	_DSS(ph)TSPGDYVLSVSENSR_
CRKL	Phosphorylation	S41		0.868	_DS(ph)STCPGDYVLSVSENSR_
CRKL	Phosphorylation	S107	-0.818	-1.177	_YPS(ph)PPMGSVSAPNLPTAEDNLEYVR_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
EIF2AK2	Phosphorylation	S83		0.256	_KAVS(ph)PLLLTTTNSSEGLSMGNYIGLINR_
F2R	Ubiquitylation	K421	0.836	0.568	_MDTCSSNLNNSIYK(gl)K_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
KIDINS220	Ubiquitylation	K27	0.661	0.970	_ALLEK(gl)CKDVDER_
KIDINS220	Ubiquitylation	K891	1.044	0.140	_VSQNSLGEMTK(gl)LGSK_
KIDINS220	Ubiquitylation	K895	0.219	-0.692	_LGSK(gl)TALNR_
KIDINS220	Phosphorylation	S1526	-0.369	-0.457	_LPSDEDES(ph)GTEESDNTPLLK_
KIDINS220	Phosphorylation	S1555	0.253	-0.108	_VPKS(ph)PEHSAEPIR_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAP3K1	Phosphorylation	S292		0.209	_RAPS(ph)PDGFSPYSPEETNR_
MAP3K1	Phosphorylation	S506	1.427		_SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1	Phosphorylation	S507		1.436	_SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1	Phosphorylation	S923	0.127	-0.120	_LSAS(ph)SEDISER_
MAP3K2	Phosphorylation	S153	0.506	-0.231	_RLS(ph)IIGPTSR_
MAP3K2	Phosphorylation	S163	-0.910	-0.776	_DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2	Phosphorylation	S164	-0.743	-0.966	_DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2	Phosphorylation	S239	-0.284	-0.618	_AQS(ph)YPDNHQEFSDYDNPIFEK_
MAP3K2	Phosphorylation	S331		0.008	_RRGS(ph)DIDNPTLTVM(ox)DISPPSR_
MAP3K3	Phosphorylation	S166		-0.325	_HLS(ph)VSSQNPGR_
MAP3K3	Phosphorylation	S175	0.120	-0.091	_S(ph)SPPPGYVPER_
MAP3K3	Phosphorylation	S176	0.120	-0.091	_S(ph)SPPPGYVPER_
MAP3K3	Phosphorylation	S250	-0.070		_AQS(ph)FPDNR_
MAP3K4	Ubiquitylation	K406		0.367	_DLNQK(gl)LR_
MAP3K4	Phosphorylation	S1252		-0.654	_HSS(ph)PTEERDEPAYPR_
MAP3K5	Phosphorylation	S1066		-1.241	_SISLPVPVLVEDTSSSSEYGSVS(ph)PDTELKVDPFSFK_
MAP3K5	Phosphorylation	S1113	-1.408	-0.562	_TLFLGIPDENFEDHSAPPS(ph)PEEK_
MAP3K6	Phosphorylation	S984	-0.616	-0.840	_VPEEPAAEEPAS(ph)PEESSGLSLLHQESK_
MAP3K7	Phosphorylation	S374	0.149	-0.337	_GS(ph)SVESLPPTSEGK_
MAP3K7	Phosphorylation	S375	0.171	-0.087	_GSS(ph)VESLPPTSEGK_
MAP3K7	Phosphorylation	S389	1.072	1.445	_RMS(ph)ADMSEIEAR_
MAP3K7	Phosphorylation	S439	0.246	0.198	_S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7	Ubiquitylation	K474	-0.385	-0.242	_MITTSGPTSEK(gl)PTR_
MAP3K7	Ubiquitylation	K589	-0.104		_SLSTYYQQCK(gl)K_
MAP3K7	Ubiquitylation	K590	-0.551	0.560	_K(gl)QLEVIR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PLCG1	Ubiquitylation	K300		8.031	_DLK(gl)NMLSQVNYR_
PLCG1	Ubiquitylation	K348		-0.219	_SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1	Ubiquitylation	K552		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K553		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K1063	0.864	0.355	_LTEGK(gl)IMER_
PLCG1	Phosphorylation	S1370	0.475	0.515	_AREGS(ph)FESR_
PSEN1	Phosphorylation	S313		0.844	_VSKNS(ph)KYNAESTER_
PSEN1	Ubiquitylation	K314	0.016	0.414	_NSK(gl)YNAESTER_
PSEN1	Phosphorylation	S366	-0.340	0.055	_AAVQELSS(ph)SILAGEDPEER_
PSEN1	Phosphorylation	S367	0.005	0.066	_AAVQELSSS(ph)ILAGEDPEER_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RAPGEF1	Phosphorylation	S377		0.629	_LSKS(ph)DEQLSSLDR_
TAOK2	Phosphorylation	S9	0.024	0.070	_AGS(ph)LKDPDVAELFFKDDPEK_
TGFBR1	Ubiquitylation	K449	-0.991		_VVCEQK(gl)LRPNIPNR_
TGFBR1	Ubiquitylation	K502	0.553	0.430	_TLSQLSQQEGIK(gl)M_
YWHAB	Ubiquitylation	K11	1.057	1.322	_(ac)TMDKSELVQK(gl)AK_
YWHAB	Ubiquitylation	K13	0.060	0.388	_AK(gl)LAEQAER_
YWHAB	Ubiquitylation	K70	0.558	-0.175	_VISSIEQK(gl)TER_
YWHAB	Ubiquitylation	K140		0.531	_YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB	Ubiquitylation	K159	0.300		_QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB	Ubiquitylation	K160	-0.439	-0.371	_K(gl)EMQPTHPIR_