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Query: ADAM9

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADAM9 0 -0.274 0.290 -0.290

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADAM9 Ubiquitylation K741 0.269 0.229 _SQTYESDGK(gl)NQANPSRQPGSVPR_
ADAM9 Phosphorylation T761 -0.724 -0.397 _HVSPVT(ph)PPREVPIYANR_
ADAM9 Phosphorylation S758 -0.375 -0.893 _HVS(ph)PVTPPR_
ADAM9 Ubiquitylation K781 -2.213 _FAVPTYAAK(gl)QPQQFPSRPPPPQPK_

Background Information for ADAM9:


Pubmed-ADAM9 »
Uniprot-ADAM9 »
Biogrid-ADAM9 »
ProteomicsDB-ADAM9 »

Tumorportal-ADAM9 »
COSMIC-ADAM9 »
GenomeRNAi-ADAM9 »
Genecards-ADAM9


Protein-protein Interactions for ADAM9
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIF2C Cat. description Hein, Mann, Cell 2015
Category members IP bait ADAM32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FIGF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPHA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLAMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ADAM9
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EG-like_dom IPR000742 1.74
Category members Peptidase_M12B_N IPR002870 0.08
Category members Blood-coag_inhib_Disintegrin IPR001762 0.07
Category members Peptidase_M12B IPR001590 0.04
Category members ADAM_Cys-rich IPR006586 0


Protein complexes (CORUM database) featuring ADAM9
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2346 ITGAV-ITGB5-ADAM9 complex Database 0
Category members Corum 2440 ITGA9-ITGB1-ADAM9 complex Database 0


Categories featuring ADAM9
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0051088 PMA-inducible membrane protein ectodomain proteolysis Database 0.26
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members GO Category GO:0042117 monocyte activation Database 0.24
Category members GO Category GO:0031233 intrinsic to external side of plasma membrane Database 0.23
Category members GO Category GO:0034612 response to tumor necrosis factor Database 0.21
Category members GO Category GO:0030574 collagen catabolic process Database 0.2
Category members GO Category GO:0042542 response to hydrogen peroxide Database 0.19
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0000186 activation of MAPKK activity Database 0.16
Category members GO Category GO:0006509 membrane protein ectodomain proteolysis Database 0.14
Category members GO Category GO:0022617 extracellular matrix disassembly Database 0.13
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members GO Category GO:0010042 response to manganese ion Database 0.08
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members GO Category GO:0005080 protein kinase C binding Database 0.04
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members GO Category GO:0005518 collagen binding Database 0.02
Category members Disease phenotype Cone_rod_dystrophy Cone rod dystrophy Database 0
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007160 cell-matrix adhesion Database 0
Category members GO Category GO:0007229 integrin-mediated signaling pathway Database 0
Category members GO Category GO:0008237 metallopeptidase activity Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0030216 keratinocyte differentiation Database 0
Category members GO Category GO:0033627 cell adhesion mediated by integrin Database 0
Category members GO Category GO:0033630 positive regulation of cell adhesion mediated by integrin Database 0
Category members GO Category GO:0033631 cell-cell adhesion mediated by integrin Database 0
Category members GO Category GO:0034616 response to laminar fluid shear stress Database 0
Category members GO Category GO:0043236 laminin binding Database 0
Category members GO Category GO:0050714 positive regulation of protein secretion Database 0
Category members GO Category GO:0051044 positive regulation of membrane protein ectodomain proteolysis Database 0
Category members GO Category GO:0051549 positive regulation of keratinocyte migration Database 0
Category members GO Category GO:0051592 response to calcium ion Database 0
Category members GO Category GO:0071222 cellular response to lipopolysaccharide Database 0


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