Results for the Category
metalloendopeptidase activity
(GO:0004222)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PITRM1 | 1 | -0.150 | 0.330 | 1.438 | -1.089 | |||
| PITRM1 | 1 | -0.150 | 0.330 | 1.318 | 0.065 | 0.492 | ||
| YME1L1 | 1 | -2.100 | 3.750 | -0.237 | -0.019 | |||
| MBTPS2 | 0 | 0.150 | 0.010 | |||||
| MIPEP | 0 | 0.050 | -0.300 | -2.616 | 0.708 | |||
| NRD1 | 0 | 0.850 | -0.580 | |||||
| ZMPSTE24 | 0 | 1.200 | -0.940 | 0.418 | 0.211 | |||
| MMP15 | 0 | 1.100 | -1.160 | |||||
| PMPCB | 0 | -0.260 | -0.100 | |||||
| PMPCB | 0 | -0.260 | -0.100 | -0.123 | -0.081 | 0.444 | ||
| PMPCB | 0 | -0.260 | -0.100 | -0.029 | -1.280 | |||
| ECE1 | 0 | 0.550 | 0.210 | 1.201 | 0.401 | |||
| IDE | 0 | -0.890 | 1.510 | -1.202 | ||||
| ADAM19 | 0 | -0.880 | 1.690 | |||||
| ADAM10 | 0 | 1.400 | -1.040 | -0.111 | 0.009 | |||
| UQCRC2 | 0 | -1.200 | 1.760 | 1.190 | 0.712 | 0.578 | ||
| AFG3L2 | 0 | -0.300 | 0.740 | -0.985 | -0.341 | 0.489 | 0.505 | |
| ADAM15 | 0 | -1.250 | 1.050 | -2.965 | ||||
| ADAM17 | 0 | 0.520 | -0.620 | |||||
| ADAMTS1 | 0 | -0.440 | 0.580 | -0.624 | ||||
| PMPCA | 0 | -0.140 | 0.680 | 0.865 | -0.098 | 0.972 | 0.919 | |
| ADAM9 | 0 | 0.290 | -0.290 | |||||
| THOP1 | 0 | 1.750 | -0.990 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ADAM10 | Ubiquitylation | K721 | -2.406 | _LPPPKPLPGTLK(gl)R_ | |
| ADAM15 | Ubiquitylation | K59 | -1.920 | _K(gl)VLQTSLPEPLR_ | |
| ADAM15 | Ubiquitylation | K729 | -0.467 | -0.591 | _LCQLK(gl)GPTCQYR_ |
| ADAM17 | Phosphorylation | S791 | -0.594 | 0.152 | _S(ph)FEDLTDHPVTR_ |
| ADAM19 | Ubiquitylation | K919 | -0.356 | 0.874 | _AGGMISSK(gl)_ |
| ADAM9 | Ubiquitylation | K741 | 0.269 | 0.229 | _SQTYESDGK(gl)NQANPSRQPGSVPR_ |
| ADAM9 | Phosphorylation | S758 | -0.375 | -0.893 | _HVS(ph)PVTPPR_ |
| ADAM9 | Phosphorylation | T761 | -0.724 | -0.397 | _HVSPVT(ph)PPREVPIYANR_ |
| ADAM9 | Ubiquitylation | K781 | -2.213 | _FAVPTYAAK(gl)QPQQFPSRPPPPQPK_ | |
| AFG3L2 | Ubiquitylation | K208 | -1.392 | _GVVDRLEVVNK(gl)R_ | |
| ECE1 | Ubiquitylation | K177 | 0.969 | _K(gl)AQVYYR_ | |
| ECE1 | Ubiquitylation | K197 | -0.049 | _AK(gl)PLMELIER_ | |
| ECE1 | Ubiquitylation | K639 | -1.498 | _NSSVEAFK(gl)R_ | |
| IDE | Ubiquitylation | K308 | -0.121 | 0.325 | _IVPIK(gl)DIR_ |
| MBTPS2 | Ubiquitylation | K363 | 0.586 | _K(gl)AVEATQVCR_ | |
| MMP15 | Phosphorylation | S589 | -0.195 | _WPDVARPPFNPHGGAEPGADS(ph)AEGDVGDGDGDFGAGVNK_ | |
| MMP15 | Ubiquitylation | K662 | 0.150 | 0.485 | _VLLYCK(gl)R_ |
| NRD1 | Phosphorylation | S86 | 0.650 | _LGADES(ph)EEEGRRGSLSNAGDPEIVK_ | |
| NRD1 | Phosphorylation | S94 | 0.185 | 0.340 | _RGS(ph)LSNAGDPEIVK_ |
| NRD1 | Phosphorylation | S96 | 0.250 | _LGADESEEEGRRGSLS(ph)NAGDPEIVK_ | |
| NRD1 | Ubiquitylation | K352 | 1.142 | _YFK(gl)EALDR_ | |
| NRD1 | Ubiquitylation | K1061 | 1.043 | _YNSEVVDK(gl)K_ | |
| NRD1 | Ubiquitylation | K1062 | 0.828 | _YNSEVVDKK(gl)_ | |
| PITRM1 | Ubiquitylation | K944 | 2.504 | _AVDWAK(gl)SGK_ | |
| PMPCA | Ubiquitylation | K232 | -1.131 | -0.941 | _FCPTENVAK(gl)INR_ |
| PMPCA | Ubiquitylation | K299 | -0.658 | _SVAQYTGGIAK(gl)LER_ | |
| PMPCA | Ubiquitylation | K478 | -2.019 | _NVKPEDVK(gl)R_ | |
| PMPCA | Ubiquitylation | K483 | -1.110 | _VASK(gl)MLR_ | |
| PMPCB | Ubiquitylation | K456 | -1.174 | _EVCTK(gl)YIYNR_ | |
| THOP1 | Ubiquitylation | K45 | 1.039 | _ELIEQTK(gl)R_ | |
| THOP1 | Ubiquitylation | K317 | -0.699 | _AVILELK(gl)R_ | |
| UQCRC2 | Ubiquitylation | K250 | -0.825 | _GGLGLSGAK(gl)ANYR_ | |
| UQCRC2 | Ubiquitylation | K377 | -1.458 | _TIAQGNLSNTDVQAAKNK(gl)_ | |
| YME1L1 | Ubiquitylation | K370 | -0.462 | _FTILGGK(gl)LPK_ | |
| YME1L1 | Ubiquitylation | K618 | -1.934 | _DAMPINK(gl)ATIMPR_ | |
| ZMPSTE24 | Ubiquitylation | K66 | -0.494 | _TTTHVPPELGQIMDSETFEK(gl)SR_ | |
| ZMPSTE24 | Ubiquitylation | K259 | -0.055 | _VYVVEGSK(gl)R_ | |
| ZMPSTE24 | Ubiquitylation | K314 | -0.581 | -0.196 | _NEEEGNSEEIK(gl)AK_ |
| ZMPSTE24 | Ubiquitylation | K470 | -0.149 | _LQALK(gl)TMK_ |
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© Copyright Svejstrup Laboratory 2015