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Query: AFG3L2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AFG3L2 0 -0.984 -0.300 0.740 -0.985 -0.341 0.489 0.505

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AFG3L2 Ubiquitylation K208 -1.392 _GVVDRLEVVNK(gl)R_

Background Information for AFG3L2:


Pubmed-AFG3L2 »
Uniprot-AFG3L2 »
Biogrid-AFG3L2 »
ProteomicsDB-AFG3L2 »

Tumorportal-AFG3L2 »
COSMIC-AFG3L2 »
GenomeRNAi-AFG3L2 »
Genecards-AFG3L2


Protein-protein Interactions for AFG3L2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait ELL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GBA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSPA14 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM45 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TGS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait USF1;usf1 Cat. description Hein, Mann, Cell 2015


Protein Domains in AFG3L2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ATPase_AAA_core IPR003959 0.14
Category members Peptidase_M41 IPR000642 0
Category members FtsH IPR005936 0
Category members Pept_M41_FtsH_extracell IPR011546 0


Protein complexes (CORUM database) featuring AFG3L2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AFG3L2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0040014 regulation of multicellular organism growth Database 0.35
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0008053 mitochondrial fusion Database 0.27
Category members GO Category GO:0042552 myelination Database 0.16
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0007528 neuromuscular junction development Database 0
Category members GO Category GO:0016265 death Database 0
Category members GO Category GO:0021675 nerve development Database 0
Category members GO Category GO:0034982 mitochondrial protein processing Database 0
Category members GO Category GO:0042407 cristae formation Database 0
Category members GO Category GO:0048747 muscle fiber development Database 0
Category members GO Category GO:0060013 righting reflex Database 0


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