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Query: ADAM15

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADAM15 0 -2.973 -1.250 1.050 -2.965

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADAM15 Ubiquitylation K729 -0.467 -0.591 _LCQLK(gl)GPTCQYR_
ADAM15 Ubiquitylation K59 -1.920 _K(gl)VLQTSLPEPLR_

Background Information for ADAM15:


Pubmed-ADAM15 »
Uniprot-ADAM15 »
Biogrid-ADAM15 »
ProteomicsDB-ADAM15 »

Tumorportal-ADAM15 »
COSMIC-ADAM15 »
GenomeRNAi-ADAM15 »
Genecards-ADAM15


Protein-protein Interactions for ADAM15
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAM33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ADAM15
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EG-like_dom IPR000742 1.74
Category members Peptidase_M12B_N IPR002870 0.08
Category members Blood-coag_inhib_Disintegrin IPR001762 0.07
Category members Peptidase_M12B IPR001590 0.04
Category members ADAM_Cys-rich IPR006586 0


Protein complexes (CORUM database) featuring ADAM15
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2359 ITGAV-ITGB3-ADAM15 complex Database 0
Category members Corum 2384 ITGA5-ITGB1-ADAM15 complex Database 0
Category members Corum 2445 ITGA9-ITGB1-ADAM15 complex Database 0


Categories featuring ADAM15
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0005912 adherens junction Database 0.25
Category members GO Category GO:0030574 collagen catabolic process Database 0.2
Category members Pathway Pathway_426 PID_INTEGRIN_A9B1_PATHWAY 0 0
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0001669 acrosomal vesicle Database 0
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007160 cell-matrix adhesion Database 0
Category members GO Category GO:0008237 metallopeptidase activity Database 0
Category members GO Category GO:0012505 endomembrane system Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0042246 tissue regeneration Database 0
Category members GO Category GO:0042995 cell projection Database 0
Category members GO Category GO:0060317 cardiac epithelial to mesenchymal transition Database 0


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