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Query: MBTPS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MBTPS2 0 0.586 0.150 0.010

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MBTPS2 Ubiquitylation K363 0.586 _K(gl)AVEATQVCR_

Background Information for MBTPS2:





Protein-protein Interactions for MBTPS2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IL17RC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBTPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MBTPS2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PDZ IPR001478 0.15


Protein complexes (CORUM database) featuring MBTPS2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MBTPS2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_915 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA 0 0.31
Category members GO Category GO:0008203 cholesterol metabolic process Database 0.08
Category members Disease phenotype Keratosis_follicularis_spinulosa_decalvans Keratosis follicularis spinulosa decalvans Database 0
Category members Disease phenotype KERATOSIS_FOLLICULARIS_SPINULOSA_DECALVANS_X-LINKED KERATOSIS FOLLICULARIS SPINULOSA DECALVANS X-LINKED Database 0
Category members Disease phenotype Mutilating_palmoplantar_keratoderma_with_periorificial_keratotic_plaques Mutilating palmoplantar keratoderma with periorificial keratotic plaques Database 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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