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Query: MMP15

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MMP15 0 0.440 1.100 -1.160

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MMP15 Ubiquitylation K662 0.150 0.485 _VLLYCK(gl)R_
MMP15 Phosphorylation S589 -0.195 _WPDVARPPFNPHGGAEPGADS(ph)AEGDVGDGDGDFGAGVNK_

Background Information for MMP15:


Pubmed-MMP15 »
Uniprot-MMP15 »
Biogrid-MMP15 »
ProteomicsDB-MMP15 »

Tumorportal-MMP15 »
COSMIC-MMP15 »
GenomeRNAi-MMP15 »
Genecards-MMP15


Protein-protein Interactions for MMP15
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in MMP15
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_Metallo IPR006026 0.03
Category members Hemopexin-like_dom IPR000585 0
Category members Pept_M10_metallopeptidase IPR001818 0
Category members Peptidoglycan-bd-like IPR002477 0
Category members Pept_M54_archaemetzincn IPR012962 0
Category members Pept_M10A_stromelysin-type IPR016293 0
Category members Hemopexin-like_repeat IPR018487 0
Category members Pept_M10A IPR021190 0
Category members Pept_M10A_metallopeptidase_C IPR021805 0


Protein complexes (CORUM database) featuring MMP15
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MMP15
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0043085 positive regulation of catalytic activity Database 0.78
Category members GO Category GO:0031012 extracellular matrix Database 0.45
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0030574 collagen catabolic process Database 0.2
Category members GO Category GO:0008047 enzyme activator activity Database 0.15
Category members GO Category GO:0022617 extracellular matrix disassembly Database 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Pathway Pathway_415 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION 0 0.09
Category members Pathway Pathway_928 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX 0 0
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008237 metallopeptidase activity Database 0
Category members GO Category GO:0032355 response to estradiol Database 0


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