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Query: UQCRC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UQCRC2 0 3.415 -1.200 1.760 1.190 0.712 0.578

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UQCRC2 Ubiquitylation K250 -0.825 _GGLGLSGAK(gl)ANYR_
UQCRC2 Ubiquitylation K377 -1.458 _TIAQGNLSNTDVQAAKNK(gl)_

Background Information for UQCRC2:


Pubmed-UQCRC2 »
Uniprot-UQCRC2 »
Biogrid-UQCRC2 »
ProteomicsDB-UQCRC2 »

Tumorportal-UQCRC2 »
COSMIC-UQCRC2 »
GenomeRNAi-UQCRC2 »
Genecards-UQCRC2


Protein-protein Interactions for UQCRC2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CSK Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ERCC6L Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM82A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait HUWE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UQCRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UQCRH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UQCRQ Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UQCRC2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_M16_C IPR007863 0.28
Category members Metalloenz_LuxS/M16 IPR011249 0.28
Category members Pept_M16_N IPR011765 0.28


Protein complexes (CORUM database) featuring UQCRC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UQCRC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_50 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ 0 0.7
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_49 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT 0 0.17
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0009060 aerobic respiration Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members GO Category GO:0005750 mitochondrial respiratory chain complex III Database 0.07
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members Pathway Pathway_198 KEGG_CARDIAC_MUSCLE_CONTRACTION 0 0
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members Pathway Pathway_30 KEGG_OXIDATIVE_PHOSPHORYLATION 0 0
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Disease phenotype Isolated_CoQ-cytochrome_C_reductase_deficiency Isolated CoQ-cytochrome C reductase deficiency Database 0
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006119 oxidative phosphorylation Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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