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Query: YME1L1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
YME1L1 1 3.032 -2.100 3.750 -0.237 -0.019

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
YME1L1 Ubiquitylation K370 -0.462 _FTILGGK(gl)LPK_
YME1L1 Ubiquitylation K618 -1.934 _DAMPINK(gl)ATIMPR_

Background Information for YME1L1:


Pubmed-YME1L1 »
Uniprot-YME1L1 »
Biogrid-YME1L1 »
ProteomicsDB-YME1L1 »

Tumorportal-YME1L1 »
COSMIC-YME1L1 »
GenomeRNAi-YME1L1 »
Genecards-YME1L1


Protein-protein Interactions for YME1L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP4E1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ENTHD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ERCC6L Cat. description Hein, Mann, Cell 2015
Category members IP bait GEMIN7 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2C Cat. description Hein, Mann, Cell 2015
Category members IP bait NCAPH Cat. description Hein, Mann, Cell 2015
Category members IP bait PFDN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait SHCBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TBC1D9 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait TTC25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in YME1L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ATPase_AAA_core IPR003959 0.14
Category members Peptidase_M41 IPR000642 0
Category members FtsH IPR005936 0


Protein complexes (CORUM database) featuring YME1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring YME1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0006515 misfolded or incompletely synthesized protein catabolic process Database 0.04
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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