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Query: ZMPSTE24

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZMPSTE24 0 0.080 1.200 -0.940 0.418 0.211

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZMPSTE24 Ubiquitylation K259 -0.055 _VYVVEGSK(gl)R_
ZMPSTE24 Ubiquitylation K470 -0.149 _LQALK(gl)TMK_
ZMPSTE24 Ubiquitylation K314 -0.581 -0.196 _NEEEGNSEEIK(gl)AK_
ZMPSTE24 Ubiquitylation K66 -0.494 _TTTHVPPELGQIMDSETFEK(gl)SR_

Background Information for ZMPSTE24:





Protein-protein Interactions for ZMPSTE24

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFB4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FDPS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDPD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GJB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC17A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC18A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC2A5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAC14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZMPSTE24

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_M48 IPR001915 0


Protein complexes (CORUM database) featuring ZMPSTE24

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ZMPSTE24

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005637 nuclear inner membrane Database 1.98
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0006998 nuclear envelope organization Database 0.4
Category members GO Category GO:0008235 metalloexopeptidase activity Database 0.33
Category members Disease phenotype HUTCHINSON-GILFORD_PROGERIA_SYNDROME HUTCHINSON-GILFORD PROGERIA SYNDROME Database 0
Category members Disease phenotype Lethal_restrictive_dermopathy Lethal restrictive dermopathy Database 0
Category members Disease phenotype RESTRICTIVE_DERMOPATHY_LETHAL RESTRICTIVE DERMOPATHY LETHAL Database 0
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0030327 prenylated protein catabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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