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Query: ECE1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ECE1 0 2.571 0.550 0.210 1.201 0.401

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ECE1 Ubiquitylation K177 0.969 _K(gl)AQVYYR_
ECE1 Ubiquitylation K197 -0.049 _AK(gl)PLMELIER_
ECE1 Ubiquitylation K639 -1.498 _NSSVEAFK(gl)R_

Background Information for ECE1:


Pubmed-ECE1 »
Uniprot-ECE1 »
Biogrid-ECE1 »
ProteomicsDB-ECE1 »

Tumorportal-ECE1 »
COSMIC-ECE1 »
GenomeRNAi-ECE1 »
Genecards-ECE1


Protein-protein Interactions for ECE1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C7orf69 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FUT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ECE1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_M13_N IPR008753 0
Category members Peptidase_M13_C IPR018497 0


Protein complexes (CORUM database) featuring ECE1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ECE1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0016485 protein processing Database 0.57
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0010815 bradykinin catabolic process Database 0.11
Category members GO Category GO:0019229 regulation of vasoconstriction Database 0.08
Category members GO Category GO:0042447 hormone catabolic process Database 0.05
Category members GO Category GO:0001921 positive regulation of receptor recycling Database 0.02
Category members GO Category GO:0031982 vesicle Database 0.01
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members Disease phenotype Hirschsprung_disease Hirschsprung disease Database 0
Category members GO Category GO:0003100 regulation of systemic arterial blood pressure by endothelin Database 0
Category members GO Category GO:0004175 endopeptidase activity Database 0
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0016486 peptide hormone processing Database 0
Category members GO Category GO:0017046 peptide hormone binding Database 0
Category members GO Category GO:0033093 Weibel-Palade body Database 0
Category members GO Category GO:0042733 embryonic digit morphogenesis Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043583 ear development Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0060037 pharyngeal system development Database 0


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