RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
PSMA5	1	0.190	0.000	-0.828		0.332	-0.038	-1.497
PSEN2	1	-1.820	3.280
CPS1	0	-0.030	-0.030
PSMA4	0
PSMA4	0			-0.383	-1.793	-0.367	-0.745	-0.334
SENP1	0	-1.070	0.900				0.519	0.698
PSEN1	0	0.930	-1.110
PSMA3	0	-0.200	0.600	-0.457	-0.083	0.518	-0.230	-1.397
PSMA6	0			-0.525	0.954	0.421	0.792	0.604
PSMA7	0	-0.630	1.250	-0.391		0.229	-0.396	-0.186
PSMA2	0			-0.344		0.665
TMEM59	0	1.350	-0.820
ECE1	0	0.550	0.210				1.201	0.401
PSMA1	0			-0.527		-0.118	-0.826	-0.205
ACE2	0	0.740	-0.320
TPP2	0	1.800	-0.220		-0.100	-0.618
ADAM10	0	1.400	-1.040				-0.111	0.009
PCSK6	0	0.020	-0.380
FURIN	0	1.280	-0.730
MBTPS1	0	0.820	-0.630
PSMB6	0			-0.608		-0.008	-0.557	0.110
PSMA8	0	-0.590	0.400	-0.391		0.229	-0.396	-0.186
NCSTN	0	-1.540	2.100				0.618	0.379
TPP1	0	-0.540	0.760	0.431			1.429	1.399

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ACE2	Phosphorylation	S645	0.672	0.846	_S(ph)SVAYAMRQYFLK_
ADAM10	Ubiquitylation	K721	-2.406		_LPPPKPLPGTLK(gl)R_
CPS1	Phosphorylation	S1278	-0.511	-1.077	_ASRSFPFVS(ph)K_
ECE1	Ubiquitylation	K177		0.969	_K(gl)AQVYYR_
ECE1	Ubiquitylation	K197		-0.049	_AK(gl)PLMELIER_
ECE1	Ubiquitylation	K639		-1.498	_NSSVEAFK(gl)R_
FURIN	Ubiquitylation	K789	-1.074	-0.470	_TAFIK(gl)DQSAL_
MBTPS1	Ubiquitylation	K124		0.229	_AGLLTLEDHPNIK(gl)R_
NCSTN	Ubiquitylation	K110		1.107	_DLMEK(gl)LK_
PCSK6	Ubiquitylation	K573		-0.143	_SQLLAK(gl)R_
PSEN1	Phosphorylation	S313		0.844	_VSKNS(ph)KYNAESTER_
PSEN1	Ubiquitylation	K314	0.016	0.414	_NSK(gl)YNAESTER_
PSEN1	Phosphorylation	S366	-0.340	0.055	_AAVQELSS(ph)SILAGEDPEER_
PSEN1	Phosphorylation	S367	0.005	0.066	_AAVQELSSS(ph)ILAGEDPEER_
PSEN2	Phosphorylation	S58	-0.112	-0.130	_TSLM(ox)SAES(ph)PTPR_
PSMA1	Ubiquitylation	K39	0.520	0.441	_QGSATVGLK(gl)SK_
PSMA1	Ubiquitylation	K41	-0.003		_SK(gl)THAVLVALK_
PSMA1	Ubiquitylation	K50	0.184		_THAVLVALK(gl)R_
PSMA1	Ubiquitylation	K61	1.405		_AQSELAAHQK(gl)K_
PSMA1	Ubiquitylation	K115	-0.377	0.087	_LVSLIGSK(gl)TQIPTQR_
PSMA1	Ubiquitylation	K208	-0.998		_ETLPAEQDLTTK(gl)NVSIGIVGK_
PSMA1	Ubiquitylation	K256		-2.626	_AQPAQPADEPAEK(gl)ADEPMEH_
PSMA2	Ubiquitylation	K50		-1.081	_AANGVVLATEK(gl)K_
PSMA2	Ubiquitylation	K51		-0.660	_AANGVVLATEKK(gl)_
PSMA2	Ubiquitylation	K53	-2.456	-0.806	_QK(gl)SILYDER_
PSMA2	Ubiquitylation	K64	-1.398	-0.958	_SVHK(gl)VEPITK_
PSMA2	Ubiquitylation	K70	-0.584		_VEPITK(gl)HIGLVYSGMGPDYR_
PSMA2	Ubiquitylation	K165	-0.769	-0.362	_ATAMGK(gl)NYVNGK_
PSMA2	Ubiquitylation	K171	-0.681	-0.416	_NYVNGK(gl)TFLEK(gl)R_
PSMA2	Ubiquitylation	K176		-0.342	_NYVNGK(gl)TFLEK(gl)R_
PSMA3	Ubiquitylation	K43	-0.394		_CK(gl)DGVVFGVEK_
PSMA3	Ubiquitylation	K57	-0.251	0.398	_LVLSK(gl)LYEEGSNKR_
PSMA3	Ubiquitylation	K65	0.202	0.516	_LYEEGSNK(gl)R_
PSMA3	Ubiquitylation	K174		-0.293	_QAAK(gl)TEIEK_
PSMA3	Ubiquitylation	K179		-0.010	_TEIEK(gl)LQMK_
PSMA3	Ubiquitylation	K183	-0.935	0.097	_LQMK(gl)EMTCR_
PSMA3	Ubiquitylation	K192	-0.190	0.526	_DIVK(gl)EVAK_
PSMA3	Ubiquitylation	K208	-0.430		_IIYIVHDEVKDK(gl)_
PSMA3	Phosphorylation	S250	0.438	0.372	_ESLKEEDES(ph)DDDNM_
PSMA4	Ubiquitylation	K176	1.345	0.502	_ATCIGNNSAAAVSMLK(gl)QDYK_
PSMA4	Ubiquitylation	K180		-0.775	_QDYK(gl)EGEMTLK_
PSMA4	Ubiquitylation	K199	-0.456	0.252	_VLNK(gl)TMDVSK_
PSMA4	Ubiquitylation	K205		-0.630	_TMDVSK(gl)LSAEK_
PSMA4	Ubiquitylation	K210		-1.092	_LSAEK(gl)VEIATLTR_
PSMA4	Ubiquitylation	K222	-1.085	0.196	_ENGK(gl)TVIR_
PSMA4	Ubiquitylation	K231	-0.975	-0.228	_QK(gl)EVEQLIK_
PSMA4	Ubiquitylation	K238	-1.175	-0.141	_QKEVEQLIK(gl)K_
PSMA5	Phosphorylation	S16	0.437	0.327	_GVNTFS(ph)PEGR_
PSMA5	Phosphorylation	T55	1.635	0.149	_IT(ph)SPLMEPSSIEK_
PSMA5	Phosphorylation	S56	1.475	1.212	_ITS(ph)PLMEPSSIEK_
PSMA5	Ubiquitylation	K91		-0.653	_TLIDK(gl)AR_
PSMA5	Ubiquitylation	K187	-0.327	-0.361	_AIGSASEGAQSSLQEVYHK(gl)SMTLK_
PSMA5	Ubiquitylation	K192	0.384	0.558	_SMTLK(gl)EAIK_
PSMA5	Ubiquitylation	K196	-0.899	-0.177	_EAIK(gl)SSLIILK_
PSMA5	Ubiquitylation	K203		-0.437	_SSLIILK(gl)QVMEEK_
PSMA6	Ubiquitylation	K45	-0.348	0.048	_GK(gl)DCAVIVTQK_
PSMA6	Ubiquitylation	K55	-0.129	0.038	_GKDCAVIVTQKK(gl)_
PSMA6	Ubiquitylation	K102	0.229	0.506	_YEAANWK(gl)YK_
PSMA6	Ubiquitylation	K104		0.926	_YEAANWK(gl)YK_
PSMA6	Ubiquitylation	K116	-1.065	-0.664	_YGYEIPVDMLCK(gl)R_
PSMA6	Ubiquitylation	K170	-0.696		_CDPAGYYCGFK(gl)ATAAGVK_
PSMA6	Ubiquitylation	K177	-0.464	-0.324	_ATAAGVK(gl)QTESTSFLEK_
PSMA6	Ubiquitylation	K187	0.017		_QTESTSFLEK(gl)K_
PSMA6	Ubiquitylation	K188	-0.004	-0.098	_QTESTSFLEKK(gl)_
PSMA7	Ubiquitylation	K28	-0.017	0.505	_K(gl)GSTAVGVR_
PSMA7	Ubiquitylation	K48	-0.697		_K(gl)SVAKLQDER_
PSMA7	Ubiquitylation	K52	-0.191	-0.218	_SVAK(gl)LQDER_
PSMA7	Ubiquitylation	K115	0.538	0.588	_YIASLK(gl)QR_
PSMA7	Ubiquitylation	K157	-0.229	-0.037	_LYQTDPSGTYHAWK(gl)ANAIGR_
PSMA7	Ubiquitylation	K218	-0.242	-0.114	_DQSLK(gl)ILNPEEIEK_
PSMA8	Ubiquitylation	K28	-0.017	0.505	_K(gl)GSTAVGVR_
PSMA8	Ubiquitylation	K48	-0.697		_K(gl)SVAKLQDER_
PSMA8	Ubiquitylation	K52	-0.191	-0.218	_SVAK(gl)LQDER_
PSMA8	Ubiquitylation	K115	0.538	0.588	_YIASLK(gl)QR_
PSMA8	Ubiquitylation	K157	-0.229	-0.037	_LYQTDPSGTYHAWK(gl)ANAIGR_
PSMA8	Ubiquitylation	K218	-0.242	-0.114	_DQSLK(gl)ILNPEEIEK_
SENP1	Ubiquitylation	K231	-0.099		_NTLK(gl)DSLFK_
TMEM59	Ubiquitylation	K206		-0.063	_ESSLSK(gl)MSYLQMR_
TMEM59	Ubiquitylation	K302	-2.229	-0.900	_SK(gl)TEDHEEAGPLPTK(gl)VNLAHSEI_
TMEM59	Ubiquitylation	K315	-1.591	-0.691	_TEDHEEAGPLPTK(gl)VNLAHSEI_
TPP2	Ubiquitylation	K1213	1.399	0.573	_GLK(gl)FATK_
TPP2	Ubiquitylation	K1217	-0.014		_FATK(gl)LVEEKPTK_
TPP2	Ubiquitylation	K1225	0.585		_LVEEKPTK(gl)ENWK_