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Query: ACE2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACE2 0 1.518 0.740 -0.320

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ACE2 Phosphorylation S645 0.672 0.846 _S(ph)SVAYAMRQYFLK_

Background Information for ACE2:





Protein-protein Interactions for ACE2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AAMP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ACE2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_M2 IPR001548 0.21


Protein complexes (CORUM database) featuring ACE2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ACE2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0001618 virus receptor activity Database 0.83
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0008241 peptidyl-dipeptidase activity Database 0.21
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0045121 membrane raft Database 0.11
Category members GO Category GO:0019229 regulation of vasoconstriction Database 0.08
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members GO Category GO:0046718 viral entry into host cell Database 0.04
Category members GO Category GO:0002005 angiotensin catabolic process in blood Database 0.01
Category members Pathway Pathway_1187 BIOCARTA_ACE2_PATHWAY 0 0
Category members Pathway Pathway_454 KEGG_RENIN_ANGIOTENSIN_SYSTEM 0 0
Category members GO Category GO:0001817 regulation of cytokine production Database 0
Category members GO Category GO:0001948 glycoprotein binding Database 0
Category members GO Category GO:0002003 angiotensin maturation Database 0
Category members GO Category GO:0003051 angiotensin-mediated drinking behavior Database 0
Category members GO Category GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin Database 0
Category members GO Category GO:0004175 endopeptidase activity Database 0
Category members GO Category GO:0004180 carboxypeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008237 metallopeptidase activity Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0017046 peptide hormone binding Database 0
Category members GO Category GO:0032800 receptor biosynthetic process Database 0
Category members GO Category GO:0042277 peptide binding Database 0
Category members GO Category GO:0042312 regulation of vasodilation Database 0
Category members GO Category GO:0046813 receptor-mediated virion attachment to host cell Database 0
Category members GO Category GO:0050727 regulation of inflammatory response Database 0


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