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Query: TMEM59

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMEM59 0 -1.617 1.350 -0.820

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMEM59 Ubiquitylation K206 -0.025 _ESSLSK(gl)MSSDLQMR_
TMEM59 Ubiquitylation K206 -0.063 _ESSLSK(gl)MSYLQMR_
TMEM59 Ubiquitylation K315 -1.591 -0.691 _TEDHEEAGPLPTK(gl)VNLAHSEI_
TMEM59 Ubiquitylation K302 -2.229 -0.900 _SK(gl)TEDHEEAGPLPTK(gl)VNLAHSEI_

Background Information for TMEM59:





Protein-protein Interactions for TMEM59

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IL20RB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TMEM59

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Prot_inh_Kunz-m IPR002223 0.05
Category members Uncharacterised_TMEM59 IPR022065 0


Protein complexes (CORUM database) featuring TMEM59

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMEM59

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0004867 serine-type endopeptidase inhibitor activity Database 1.42
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0005770 late endosome Database 0.09
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0004175 endopeptidase activity Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0010508 positive regulation of autophagy Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0


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