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Query: TPP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TPP2 0 1.254 1.800 -0.220 -0.100 -0.618

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TPP2 Ubiquitylation K1213 1.399 0.573 _GLK(gl)FATK_
TPP2 Ubiquitylation K1217 -0.014 _FATK(gl)LVEEKPTK_
TPP2 Ubiquitylation K1225 0.585 _LVEEKPTK(gl)ENWK_

Background Information for TPP2:


Pubmed-TPP2 »
Uniprot-TPP2 »
Biogrid-TPP2 »
ProteomicsDB-TPP2 »

Tumorportal-TPP2 »
COSMIC-TPP2 »
GenomeRNAi-TPP2 »
Genecards-TPP2


Protein-protein Interactions for TPP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C9orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHIA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DENND2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KBTBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL36 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAA40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TPP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_S8/S53_dom IPR000209 0
Category members Peptidase_S8_subtilisin-rel IPR015500 0


Protein complexes (CORUM database) featuring TPP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TPP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0002474 antigen processing and presentation of peptide antigen via MHC class I Database 2.5
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0008240 tripeptidyl-peptidase activity Database 0.27
Category members GO Category GO:0004177 aminopeptidase activity Database 0.13
Category members GO Category GO:0004252 serine-type endopeptidase activity Database 0.05
Category members GO Category GO:0004175 endopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0


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