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Query: PMPCA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PMPCA 0 1.548 -0.140 0.680 0.865 -0.098 0.972 0.919

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PMPCA Ubiquitylation K299 -0.658 _SVAQYTGGIAK(gl)LER_
PMPCA Ubiquitylation K232 -1.131 -0.941 _FCPTENVAK(gl)INR_
PMPCA Ubiquitylation K483 -1.110 _VASK(gl)MLR_
PMPCA Ubiquitylation K478 -2.019 _NVKPEDVK(gl)R_

Background Information for PMPCA:


Pubmed-PMPCA »
Uniprot-PMPCA »
Biogrid-PMPCA »
ProteomicsDB-PMPCA »

Tumorportal-PMPCA »
COSMIC-PMPCA »
GenomeRNAi-PMPCA »
Genecards-PMPCA


Protein-protein Interactions for PMPCA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C4orf26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CA5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC69 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTPBP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGIX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMPCA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNMTL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PMPCA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_M16_C IPR007863 0.28
Category members Metalloenz_LuxS/M16 IPR011249 0.28
Category members Pept_M16_N IPR011765 0.28


Protein complexes (CORUM database) featuring PMPCA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PMPCA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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